Fenazona

Fenazona Uses, Dosage, Side Effects, Food Interaction and all others data.

An analgesic and antipyretic that has been given by mouth and as ear drops. Fenazona is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Fenazona is an analgesic and antipyretic that has been given by mouth and as ear drops. Fenazona is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Trade Name Fenazona
Generic Antipyrine
Antipyrine Other Names Analgesine, Antipyrine, Fenazon, Fenazona, Phenazon, Phenazone
Type
Formula C11H12N2O
Weight Average: 188.2258
Monoisotopic: 188.094963016
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Fenazona
Fenazona

Uses

Fenazona is an antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.

Fenazona is an analgesic often used to test effects of other drugs on liver enzymes.

In combination with benzocaine in otic solutions, antipyrine is indicated for the symptomatic relief of acute otitis media arising from various etiologies.

Fenazona is also used to associated treatment for these conditions: Cough, Otitis Media (OM), Buccopharyngeal anesthesia

How Fenazona works

Fenazona is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis.

Food Interaction

  • Take with or without food. When taken after meals, the Cmax and Tmax of oral antipyrine are reduced, but the overall bioavailability is not significantly impacted.

Innovators Monograph

You find simplified version here Fenazona

*** Taking medicines without doctor's advice can cause long-term problems.
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