Ecanol Vag

Ecanol Vag Uses, Dosage, Side Effects, Food Interaction and all others data.

Ecanol Vag modifies the permeability of cell wall membrane in fungi; may interfere with RNA and protein synthesis, and lipid metabolism.

Ecanol Vag is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Ecanol Vag prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.

Trade Name Ecanol Vag
Availability Prescription only
Generic Econazole
Econazole Other Names Econazol, Econazole
Related Drugs nystatin topical, gentamicin topical, clotrimazole topical, ketoconazole topical, terbinafine, terbinafine topical, itraconazole, mupirocin topical, miconazole topical, Lamisil
Type Tablet
Formula C18H15Cl3N2O
Weight Average: 381.684
Monoisotopic: 380.024996233
Groups Approved
Therapeutic Class Drugs used in Vaginal and Vulval condition, Topical Antifungal preparations
Manufacturer Abbott Healthcare Pvt Ltd
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Ecanol Vag
Ecanol Vag


Ecanol Vag Cream: All fungal skin infections due to dermatophytes, yeasts, moulds and other fungi. These include Vulvo-vaginal candidiasis, Candidial napkin rash, and other candidial infection, Ringworm (tinea) infections, Athlete's foot, Paronychia, Pityriasis versicolor and Balanitis.

Ecanol Vag-G Cream: Vulvo-vaginal candidiasis or any other fungal infection of vagina.

Ecanol Vag VT: Vulvo-vaginal candidiasis or any other fungal infection of vagina.

For the treatment of onychomycosis, local therapy with Ecanol Vag cream, combined with an oral antimycotic, is recommended.

Ecanol Vag is also used to associated treatment for these conditions: Allergy Skin, Balanitis candida, Dermatitis, Fungal infectious disorders of the Beard, Fungal skin infection, Herpes Zoster, Intertrigo, Mycotic Eczema, Pityriasis versicolor, Ringworm, Skin candida, Tinea Corporis, Tinea Cruris, Tinea Pedis, Tinea pedis of the interdigital, Vulvovaginal mycotic infection, Cutaneous candidiasis, Cutaneous dermatophyte infection

How Ecanol Vag works

Ecanol Vag interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Ecanol Vag may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.


Ecanol Vag dosage

Ecanol Vag Cream is applied to the affected skin areas once or twice daily, in the morning and/or in the evening and gently rubbed in with the clean finger.

For mycoses of the hands, application is recommended following each washing of the hands. For the treatment of onychomycosis, occlusive dressings are recommended.

Ecanol Vag-G Cream is applied with the applicator par vaginally once or twice daily.

Ecanol Vag VT is applied with the applicator par vaginally one tablet once or twice daily.

In order to prevent relapse, treatment should be continued for 2 weeks after clinical cure.

Side Effects

Rarely, transient local mild irritation, itching & redness may occur immediately after application. Ecanol Vag has minimal allergic effect. It is well tolerated, even by delicate skin. Local irritations are not likely to occur, except in rare cases, e.g., in eczematous skin areas. In such cases, anti-eczematous treatment is recommended for several days before therapy with Ecanol Vag is initiated.


Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.


Hypersensitivity has rarely been recorded. If something like this occur, administration of the product should be discontinued. The infected area should be kept clean and dry during treatment.


Although not studied, based on the chemical similarity of enconazole with other imidazole compounds, a theoretical potential for competitive interaction with compounds metabolized by CYP3A4/2C9 exists. Due to the limited systemic availability after vaginal application (see Pharmacokinetics under Actions), clinically relevant interactions are unlikely to occur, in patients on oral anticoagulants eg, warfarin and acenocoumarol, caution should be exercised and monitoring of the anticoagulant effect should be considered.

Food Interaction

No interactions found.

Elimination Route

After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.

Pregnancy & Breastfeeding use

During pregnancy: There is no information of any abnormality or adverse event in neonates while Ecanol Vag Cream / VT had been used during pregnancy.

During lactation: As the systemic absorption of Ecanol Vag Nitrate cream is extremely low after topical/vaginal use, excretion in breast milk is likely to be negligible. So, it can be used topically/vaginally during lactation if needed.


Hypersensitivity to any component of Ecanol Vag.

Acute Overdose

Ecanol Vag Cream / VT is intended for topical and vaginal use. If accidental ingestion of large quantities of the product occurs, an appropriate method of gastric emptying may be used if considered desirable.

Innovators Monograph

You find simplified version here Ecanol Vag

Ecanol Vag contains Econazole see full prescribing information from innovator Ecanol Vag Monograph, Ecanol Vag MSDS, Ecanol Vag FDA label
*** Taking medicines without doctor's advice can cause long-term problems.