Deflux DT

Deflux DT Tablet

Deflux DT is dopamine receptor (D2) antagonist which selectively inhibits dopamine at the D2 receptor. It acts principally at receptors in the chemoreceptor trigger zone (CTZ) and also at receptors in the stomach.


Stimulation of gut motility in-

  • Non-ulcer dyspepsia
  • Oesophageal reflux, reflux oesophagitis and gastritis
  • Diabetic gastroparesis
  • Functional dyspepsia
  • Speeding barium transit in follow through radiological studies

Prevention and symptomatic relief of acute nausea and vomiting from any cause including cytotoxic therapy, radiotherapy and antiparkinsonism therapy.

In the prophylactic treatment of migraine.

Deflux DT is also used to associated treatment for these conditions: Diabetic Gastroparesis, Dyspepsia, Erosive Esophagitis, Gastrointestinal Symptoms, Non-erosive Reflux Esophagitis Disease (NERD), Upper gastrointestinal motility disorders

Deflux DT

Trade Name Deflux DT
Generic Domperidone
Domperidone Other Names Domperidona, Domperidone, Domperidonum
Weight 10mg
Type Tablet
Formula C22H24ClN5O2
Weight Average: 425.911
Monoisotopic: 425.161852744
Protein binding


Therapeutic Class Motility Stimulants, Motility stimulants/Dopamine antagonist, Prokinetic drugs
Manufacturer Beximco Pharmaceuticals Ltd
Available Country Bangladesh
Last Updated: June 23, 2021 at 11:19 am


Deflux DT
Domperidone Structure


Deflux DT dosage

Adults: 10 - 20 mg every 4 - 8 hours daily

Children: 0.2 - 0.4 mg/kg every 4 - 8 hours daily.

Deflux DT tablet and suspension should be taken 15 - 30 minutes before a meal.  For acute nausea and vomiting, maximum period of treatment is 12 weeks.

Side Effects

Deflux DT may produce hyperprolactinemia which may cause galactorrhea & breast enlargement, soreness and reduced libido. It may rarely cause dry mouth, thirst, headache, nervousness, drowsiness, diarrhea, skin rash and itching.


Deflux DT should be used with absolute caution in case of children because there may be an increased risk of extra-pyramidal reactions in young children because of an incompletely developed blood brain barrier.


Deflux DT may reduce the hypoprolactinaemic effect of bromocriptine. Anti-muscarinics and opioid analgesics may antagonize the action of Deflux DT on gastrointestinal function.

Food Interaction

  • Take before a meal. Take 15-30 minutes before meals.

Half Life

7 hours

Pregnancy & Breastfeeding use

Use in pregnancy: The safety of this drug has not been established for pregnant women. So it is not recommended during pregnancy. 

Use in lactation: Deflux DT may precipitate galactorrhea and improve postnatal lactation, which is secreted in breast milk but in very small quantities insufficient to be considered harmful.


Deflux DT is contraindicated to the patients who have hypersensitivity to this drug and in case of neonates.

Acute Overdose

Overdose has been reported primarily in infants and children. Symptoms of overdosage may include disorientation, somnolence and extrapyramidal reactions. There is no specific antidote to domperidone, but in the event of overdose, the administration of activated charcoal may be useful. Anticholinergics, antiparkinson drugs may be useful in controlling extrapyramidal reactions. The patient should be observed closely and supportive measures employed.

Storage Condition

Store in a cool dry place protected from light. Keep out of reach of children.

Innovators Monograph

Deflux DT contains Domperidone see full prescribing information from innovator // generic/domperidone/domperidone-maleate-suppository-prescribing-information" Monograph