D-glucitol
D-glucitol Uses, Dosage, Side Effects, Food Interaction and all others data.
A polyhydric alcohol with about half the sweetness of sucrose. D-glucitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
| Trade Name | D-glucitol |
| Availability | Rx and/or OTC |
| Generic | Sorbitol |
| Sorbitol Other Names | D-glucitol, D-Sorbit, D-Sorbitol, G-ol, L-Gulitol, Sorbitol |
| Related Drugs | MiraLAX, Colace, docusate, Linzess, bisacodyl, senna |
| Type | |
| Formula | C6H14O6 |
| Weight | Average: 182.1718 Monoisotopic: 182.07903818 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
D-glucitol is a product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
Used as a non-stimulant laxative via an oral suspension or enema.
D-glucitol is also used to associated treatment for these conditions: Constipation, Constipation caused by Pregnancy, Occasional Constipation, Bladder irrigation therapy, Bowel preparation therapy, Preparation for rectoscopic or sigmoidoscopic examination
How D-glucitol works
D-glucitol exerts its laxative effect by drawing water into the large intestine, thereby stimulating bowel movements.
Toxicity
Acute oral toxicity (LD50): 15900 mg/kg [Rat].
Food Interaction
No interactions found.D-glucitol Disease Interaction
Major: inflammatory bowel disease, intestinal obstruction disorders, fluid expansionModerate: diabetes, sodium imbalances
Elimination Route
D-glucitol will either be excreted in the urine by the kidneys, or metabolized to carbon dioxide and dextrose.
Innovators Monograph
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