8-Diaminoacridine Uses, Dosage, Side Effects and more
3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings.
8-Diaminoacridine is an acriflavine derivative which is a disinfectant bacteriostatic against many gram-positive bacteria. 8-Diaminoacridine is toxic and carcinogenic in mammals and so it is used only as a surface disinfectant or for treating superficial wounds.
| Attribute | Details |
|---|---|
| Trade Name | 8-Diaminoacridine |
| Generic | Proflavine |
| Proflavine Other Names | 2,8-Diaminoacridine, 3,6-acridinediamine, 3,6-diaminoacridine, Diaminoacridine, Proflavin, Proflavina, Proflavine, Proflavinum |
| Type | |
| Formula | C13H11N3 |
| Weight | Average: 209.2465 Monoisotopic: 209.095297367 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
8-Diaminoacridine is a topical antiseptic agent used in wound dressings to prevent infections.
Topical antiseptic used mainly in wound dressings.
How 8-Diaminoacridine works
8-Diaminoacridine acts by interchelating DNA (intercalation), thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. This prevents bacterial reproduction.