6-acridinediamine

6-acridinediamine Uses, Dosage, Side Effects, Food Interaction and all others data.

3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings.

6-acridinediamine is an acriflavine derivative which is a disinfectant bacteriostatic against many gram-positive bacteria. 6-acridinediamine is toxic and carcinogenic in mammals and so it is used only as a surface disinfectant or for treating superficial wounds.

Trade Name 6-acridinediamine
Generic Proflavine
Proflavine Other Names 2,8-Diaminoacridine, 3,6-acridinediamine, 3,6-diaminoacridine, Diaminoacridine, Proflavin, Proflavina, Proflavine, Proflavinum
Type
Formula C13H11N3
Weight Average: 209.2465
Monoisotopic: 209.095297367
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
6-acridinediamine
6-acridinediamine

Uses

6-acridinediamine is a topical antiseptic agent used in wound dressings to prevent infections.

Topical antiseptic used mainly in wound dressings.

How 6-acridinediamine works

6-acridinediamine acts by interchelating DNA (intercalation), thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. This prevents bacterial reproduction.

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here 6-acridinediamine

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000002
http://classyfire.wishartlab.com/tax_nodes/C0001253
http://classyfire.wishartlab.com/tax_nodes/C0001908
http://classyfire.wishartlab.com/tax_nodes/C0000274
http://classyfire.wishartlab.com/tax_nodes/C0000053
http://classyfire.wishartlab.com/tax_nodes/C0000089
http://classyfire.wishartlab.com/tax_nodes/C0002448
http://classyfire.wishartlab.com/tax_nodes/C0004144
http://classyfire.wishartlab.com/tax_nodes/C0004139
http://classyfire.wishartlab.com/tax_nodes/C0002450
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:8452
http://www.hmdb.ca/metabolites/HMDB0015255
http://www.genome.jp/dbget-bin/www_bget?cpd:C11181
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=7099
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505401
https://www.chemspider.com/Chemical-Structure.6832.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=12590
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=8723
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=8452
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL55400
https://zinc.docking.org/substances/ZINC000003775644
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000995
http://www.pharmgkb.org/drug/PA164748742
https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/PRL
https://en.wikipedia.org/wiki/Proflavine
*** Taking medicines without doctor's advice can cause long-term problems.
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