Gastric tissue biopsy and culture

Gastric Tissue Biopsy and Culture: Overview

A gastric tissue biopsy and culture are two important tests used for diagnosing and evaluating diseases of the stomach. It can help in determining the presence of an infection, inflammation, or cancer. During a gastric tissue biopsy, a small piece of tissue is obtained from the stomach wall. A laboratory can then cultivate the tissue and check for any abnormalities such as an infection or cancer.

Preparation for Gastric Tissue Biopsy

Before the gastric tissue biopsy, your doctor may ask you to take some precautions such as avoiding aspirin and other anti-inflammatory medications for several days prior to the procedure. You may also be asked to temporarily stop taking certain dietary supplements. In some cases, you may have to take specific antibiotics to prevent infection.

Gastric Tissue Biopsy Procedure

During a gastric tissue biopsy, a thin, flexible tube called an endoscope is inserted through the mouth and into the stomach. The endoscope is equipped with a tiny camera and a small, lighted probe. The doctor is then able to see the entire lining of the stomach and identify any areas where a tissue sample is needed. A small piece of the tissue is then taken and sent to a laboratory for analysis.

Types of Gastric Tissue Biopsy

There are two types of gastric tissue biopsy: endoscopic biopsy and surgical biopsy. During an endoscopic biopsy, the doctor uses an endoscope to take a tissue sample. During a surgical biopsy, the doctor makes a small incision in the stomach wall and takes a tissue sample with a small forceps. Endoscopic biopsy is less invasive than surgical biopsy and is usually preferred.

Risks of Gastric Tissue Biopsy

The risks of gastric tissue biopsy are generally considered to be very low. Common side effects include bleeding, mild abdominal discomfort, and/or nausea and vomiting. Rarely, infection or damage to the stomach lining can occur. Complications associated with surgical biopsy are more serious and include potential for severe bleeding and damage to the stomach.

Why is Gastric Tissue Biopsy Necessary?

Gastric tissue biopsy is most commonly used to determine the presence of infection, inflammation, or cancer. It can help in confirming the diagnosis or ruling out certain conditions. It can also be used to determine the cause of unexplained stomach pain or discomfort.

When is Gastric Tissue Biopsy Needed?

A gastric tissue biopsy may be recommended if you experience stomach pain or unexplained weight loss, have a family history of stomach cancer, or have been diagnosed with a stomach disorder. It may also be used if tests such as endoscopies or imaging studies (e.g. CT scans) show evidence of abnormalities in the stomach lining.