17-Hydroxyprogesterone
.What is 17-Hydroxyprogesterone?
17-Hydroxyprogesterone (17-OHP) is a hormone that is produced by the adrenal glands and is involved in the regulation of many body functions. It is a metabolite of the hormone progesterone. 17-OHP levels are tested to evaluate adrenal and pituitary function, to determine if a woman is producing too much of the male hormone testosterone, to check for certain types of congenital adrenal hyperplasia, and to help diagnose abnormal sexual development in children.
Preparation for a 17-Hydroxyprogesterone Test
A 17-Hydroxyprogesterone test may not require any special preparation, although the doctor may recommend avoiding certain medications or supplements for a few days before the test. The patient may also be asked to fast for 12 hours before the test, as this can help provide more accurate results.
Procedure for the 17-Hydroxyprogesterone Test
The 17-hydroxyprogesterone test is typically done through a urine or blood sample. During the test, a health care professional will draw a sample of blood from a vein in the arm using a needle. The sample will be sent to a laboratory for testing. A urine sample may also be collected and tested.
Types of 17-Hydroxyprogesterone Tests
There are several types of tests that are used to check levels of 17-OHP in the body. These include:
- Spot urine sample test – A urine sample is collected in the morning and tested.
- Serum test – A blood sample is taken from a vein in the arm and tested.
- Saliva test – Saliva is taken from the patient and tested.
Risks of the 17-Hydroxyprogesterone Test
The 17-Hydroxyprogesterone test is a generally safe and simple procedure. The only risks associated with the test are those associated with having a blood sample drawn, such as pain, swelling, bruising, and fainting.
Why is the 17-Hydroxyprogesterone Test Performed?
The 17-Hydroxyprogesterone test is usually performed to evaluate adrenal and pituitary function, check for abnormal sexual development in children, determine if a woman is producing excess testosterone, or to diagnose certain types of congenital adrenal hyperplasia.
When is the 17-Hydroxyprogesterone Test Used?
The 17-Hydroxyprogesterone test is typically used for newborns, to check for abnormal sexual development, and to diagnose certain types of congenital adrenal hyperplasia. The 17-OHP test may also be used to evaluate adrenal and pituitary function and to determine if a woman is producing too much testosterone.