Zinc Gluconate

Zinc Gluconate Uses, Dosage, Side Effects, Food Interaction and all others data.

Zinc Gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc Gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.

Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia , , , .

Studies show that zinc may be better absorbed in humans in the gluconate form , , however, results from other studies may vary , [L27280].

Trade Name Zinc Gluconate
Generic Zinc gluconate
Zinc gluconate Other Names Zinc gluconate
Weight 10mg, 23mg, 10mg, 100mg, 15mg, 22mg, 22.5mg, 25mg, 30mg, 50mg, 60mg, 78mg
Type Oral lozenge, oral tablet
Formula C12H22O14Zn
Weight Average: 455.67
Monoisotopic: 454.030097
Protein binding

Please refer to DrugBank entry Zinc

Groups Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Zinc Gluconate
Zinc Gluconate

Uses

Zinc Gluconate is an ingredient found in a variety of supplements and vitamins.

Zinc Gluconate is mainly indicated in conditions like zinc deficiency, and can also be administered in adjunctive therapy as an alternative drug of choice in diarrhea .

Zinc Gluconate is also used to associated treatment for these conditions: Zinc Deficiency

How Zinc Gluconate works

Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV) .

Toxicity

Nausea, vomiting, diarrhea, and mouth irritation have been reported in patients ingesting zinc gluconate tablets that were dissolved in the mouth for management the common cold .

Zinc crosses the placenta and is found the cord blood and placenta. Fetal concentrations are regulated by the placenta .

For more information, refer to Please refer to DrugBank entry Zinc.

Acute: 1290 mg/kg in mouse

Food Interaction

  • Avoid milk and dairy products. Separate the use of zinc from these products by at least 2 hours before administration. Separate for 2 hours after administration if these products also contain phosphorus.
  • Do not take with bran and high fiber foods. For optimal absorption, take zinc at least 2 hours before or after eating high-fiber foods.
  • Take on an empty stomach. Take at least 1 hour before and 2 hours after eating for optimal absorption. Zinc can be taken with food to reduce gastrointestinal upset.

Volume of Distribution

Stored primarily in skeletal muscle and bone .

Elimination Route

Please refer to DrugBank entry Zinc

Half Life

280 days

Clearance

Please refer to DrugBank entry Zinc

Elimination Route

Feces and urine

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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