Sutoprofen

Sutoprofen Uses, Dosage, Side Effects, Food Interaction and all others data.

An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.

Sutoprofen is a non-steroidal anti-inflammatory analgesic and antipyretic. Ophthalmic anti-inflammatory medicines are used in the eye to lessen problems that can occur during or after some kinds of eye surgery. Sometimes, the pupil of the eye gets smaller during an operation (pupil constriction), making it more difficult for the surgeon to reach some areas of the eye. Sutoprofen is used to help prevent this.

Trade Name Sutoprofen
Generic Suprofen
Suprofen Other Names Suprofen, Suprofene, Suprofeno, Suprofenum, Sutoprofen
Type
Formula C14H12O3S
Weight Average: 260.308
Monoisotopic: 260.05071494
Protein binding

20%

Groups Approved, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Sutoprofen
Sutoprofen

Uses

Sutoprofen is an NSAID used to prevent pupil constriction in ocular surgery.

Used as eye drops to inhibit the miosis (pupil constriction) that may occur during ocular surgery.

Sutoprofen is also used to associated treatment for these conditions: Intraoperative miosis

How Sutoprofen works

Sutoprofen binds to the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes, preventing the synthesis of prostaglandins and reducing the inflammatory response. Cyclooxygenase catalyses the formation of prostaglandins and thromboxane from arachidonic acid (itself derived from the cellular phospholipid bilayer by phospholipase A2). Prostaglandins act (among other things) as messenger molecules in the process of inflammation. The overall result is a reduction in pain and inflammation in the eyes and the prevention of pupil constriction during surgery. Normally trauma to the anterior segment of the eye (especially the iris) increases endogenous prostaglandin synthesis which leads to constriction of the iris sphincter.

Toxicity

Symptoms of overdose include bleeding in the eye or redness or swelling of the eye or the eyelid, blurred vision or other change in vision, fever or chills, itching or tearing, nausea or vomiting, pain, sensitivity to light, shortness of breath, sticky or matted eyelashes, swelling of face, throbbing pain, tightness in chest, troubled breathing, and wheezing.

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here Sutoprofen

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https://en.wikipedia.org/wiki/Suprofen
*** Taking medicines without doctor's advice can cause long-term problems.
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