Spazin
Spazin Uses, Dosage, Side Effects, Food Interaction and all others data.
Tiemonium are quaternary ammonium antimuscarinic agent with peripheral effect similar to those of atropine. Tiemonium strengthens calcium bonding with phospholipids and proteins thus stabilizing the cell membrane of the GI tract.
| Trade Name | Spazin |
| Generic | Tiemonium Methylsulphate |
| Weight | 50mg |
| Type | Tablet |
| Therapeutic Class | Anticholinergics |
| Manufacturer | Euro Pharma Ltd |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Spazin is an antispasmodic drug. It reduces muscle spasms of the intestine, biliary system, uterus & urinary bladder. It is used for the pain in gastrointestinal, biliary, urinary and gynecological disease such as gastroenteritis, diarrhea, dysentery, biliary colic, enterocolitis, cholecystytis, colonopathies, mild cystitis, & spasmodic dysmenorrhoea.
Dosage
Spazin dosage
Tablet: Recommended oral dose of Spazin tablet is 2-6 tablets (100-300 mg) daily in divided dose.
Injection: Recommended injectable dose is 1 Spazin Injection 3 times daily, through Intravenous route slowly or Intramuscular route.
Syrup:
- Children: 3 mg to 6 mg/kg/day or 1.5 ml to 3 ml/kg/day in 3 divided doses.
- Adult: 30 mg to 90 mg or 15 ml to 45 ml 3 times daily or as directed by physician.
Suppository: Recommended dose is 20 mg Spazin suppository two or three times daily, through rectal route.
Side Effects
Side effect with the use of Spazin is very rare.
Precaution
Precautions should be exercised for treatment of patients with disorders of prostate, chronic bronchitis, coronary insufficiency, ambient hyperthermia, cardiac disorders, thyroid disorders, serious renal & hepatic insufficiency.
Interaction
Spazin should not be used with other drugs without prior consult of a registered physician to avoid possible drug interaction.
Pregnancy & Breastfeeding use
Spazin may be used in pregnancy only if it is clearly needed by the assessment of risk benefit ratio. Spazin may be used in lactating mother only if it is clearly needed by the assessment of risk benefit ratio.
Contraindication
Spazin should not be used in Glucoma or where acute pain of eyeball with vision disturbance was found. This drug should also not be used in patients with the disorder of prostate or urinary bladder.
Special Warning
Paediatric use: safety and effectiveness of Tiemonium methylsulphate in paediatric patients have not been established.
Geriatric use: Efficacy and safety were maintained with increasing age.
Acute Overdose
Occasional retention of urine may occur in case of overdoses.
Storage Condition
Keep it in a cool and dry place, protected from light and moisture. Keep all medicines away from the reach of the children.
Innovators Monograph
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FAQ
What is Spazin used for?
Spazin is an antispasmodic drug. It used to reduces muscle spasms of the intestine, biliary system, uterus & urinary bladder.
What are the side effects of Spazin?
Spazin may have some undesirable effects in certain individuals like risk of hypotension and tachycardia if ingested in high doses rapidly.
Is Spazin safe during pregnancy?
Spazin is not recommended during pregnancy.
Is Spazin safe during breastfeeding?
Spazin is not recommended during breastfeeding.Please discuss the risks and benefits with your doctor.
Can I drink alcohol with Spazin?
Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Spazin.
Can I drive after taking Spazin?
If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Spazin medicine then it may not be safe to drive a vehicle or operate heavy machinery.
When should not to use Spazin?
Hypersensitivity to Spazin is a contraindication. In addition,Spazin should not be used if you have the following conditions:
angle closure glaucoma,
urethro prostatic disorder.
How can used Spazin?
Spazin usual dose is 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses.
Can I overdose on Spazin?
Occasional retention of urine may occur in case of overdoses.
How does Spazin work?
Spazin prevents the effects of acetylcholine by blocking its binding to muscarinic cholinergic receptors at neuroeffector sites on smooth muscle of GI tract 2, regardless of their function and innervations.
