Sodium Dodecyl Sulfate
Sodium Dodecyl Sulfate Uses, Dosage, Side Effects, Food Interaction and all others data.
Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes. It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity.
SLS is an anionic surfactant. Its amphiphilic properties make it an ideal detergent.
| Trade Name | Sodium Dodecyl Sulfate |
| Generic | Sodium lauryl sulfate |
| Sodium lauryl sulfate Other Names | Laurylsiran sodny, NaDS, Natrium laurylsulfuricum, Sodium dodecyl sulfate, Sodium dodecyl sulphate, Sodium dodecylsulfate, Sodium laurilsulfate, Sodium lauryl sulfate, Sodium lauryl sulphate |
| Type | |
| Formula | C12H25NaO4S |
| Weight | Average: 288.379 Monoisotopic: 288.137124653 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Sodium Dodecyl Sulfate is an anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent.
SLS is used as a surfactant in shampoos and toothpastes. SLS also has microbicidal activities against both enveloped (Herpes simplex viruses, HIV-1, Semliki Forest virus) and nonenveloped (papillomaviruses, reovirus, rotavirus and poliovirus) viruses, although it has not been approved for this use.
How Sodium Dodecyl Sulfate works
Like other surfactants, SLS is amphiphilic. It thus migrates to the surface of liquids, where its alignment and aggregation with other SLS molecules lowers the surface tension. This allows for easier spreading and mixing of the liquid. SLS has potent protein denaturing activity and inhibits the infectivity of viruses by by solubilizing the viral envelope and/or by denaturing envelope and/or capsid proteins.
Toxicity
Oral (LD50): Acute: 1288 mg/kg [Rat]
Food Interaction
- Take after a meal. When Sodium Dodecyl Sulfate is formulated in paste form for oral health, it should be used after meals.
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