Sleep Aid

Sleep Aid Uses, Dosage, Side Effects, Food Interaction and all others data.

Sleep Aid is a first-generation antihistamine. It can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. Sleep Aid is also used in combination with the analgesics paracetamol (acetaminophen) and codeine as an analgesic/calmative preparation, and is prescribed in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.

Sleep Aid is an antihistamine derived from monoethanolamine possessing antimuscarinic and pronounced sedative effects.

Sleep Aid is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Sleep Aid is a member of the ethanolamine class of antihistamines and has anti-allergy power far superior to virtually every other antihistamine on the market, with the exception of diphenhydramine (Benadryl). It is also the most powerful over-the-counter sedative available in the United States, and more sedating than many prescription hypnotics. In a study, it was found to be superior to even the barbiturate, phenobarbital for use as a sedative. Sleep Aid is also a potent anticholinergic.

Trade Name Sleep Aid
Availability Rx and/or OTC
Generic Doxylamine
Doxylamine Other Names Dossilamina, Doxilamina, Doxilminio, Doxylamine, Doxylaminum
Related Drugs amoxicillin, prednisone, doxycycline, hydroxyzine, amitriptyline, lorazepam, cetirizine, cetirizine ophthalmic, cephalexin, loratadine
Type Tablet
Formula C17H22N2O
Weight Average: 270.3694
Monoisotopic: 270.173213336
Groups Approved, Vet approved
Therapeutic Class Anti-emetic drugs, Sedating Anti-histamine
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Sleep Aid
Sleep Aid

Uses

Sleep Aid is used for Hypersensitivity reactions, Insomnia

Sleep Aid is also used to associated treatment for these conditions: Common Cold, Flu Symptoms, Insomnia, Mild Allergic Rhinitis, Nausea, Vomiting

How Sleep Aid works

Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors. It also has substantial sedative and anticholinergic effects.

Dosage

Sleep Aid dosage

Hypersensitivity reactionn: 25 mg every 4-6 hr. Max: 150 mg daily.

Insomnia: 25 mg given 30 minutes before retiring at night.

Should be taken with food. Take with food or milk.

Side Effects

Acute dystonic reactions and long-lasting impaired consciousness in child. CNS depression including slight drowsiness to deep sleep, lassitude, dizziness, incoordination. Headache, psychomotor impairment and antimuscarinic effects. Rarely rashes and hypersensitivity reactions, blood disorders, convulsions, sweating, myalgia, extrapyramidal effects, tremor, confusion, tinnitus, hypotension, hair loss.

Toxicity

Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.

Precaution

May impair ability to drive and operate machinery. Angle-closure galucoma, urinary retention, prostatic hypertrophy or pyloroduodenal obstruction; epilepsy; hepatic impairment. Elderly. Lactation.

Interaction

Enhance effects of CNS depressants eg alcohol, barbiturates, hypnotics, opioid analgesics, anxiolytic sedatives and antipsychotics. Atropine, TCAs, MAOIs. Can mask signs of ototoxicity caused by aminoglycosides.

Food Interaction

  • Avoid alcohol. Co-administration may increase drowsiness and fall risk.

[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.

Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.

Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Elimination Route

Readily absorbed via the gastrointestinal tract.

Half Life

10 hours

Pregnancy & Breastfeeding use

Category A: Controlled studies in women fail to demonstrate a risk to the fetus in the 1st trimester (and there is no evidence of a risk in later trimesters), and the possibility of fetal harm remains remote.

Contraindication

Severe liver disease; avoid alcohol; premature infants or full-term neonates.

Storage Condition

Store at 15-30┬░C.

Innovators Monograph

You find simplified version here Sleep Aid

Sleep Aid contains Doxylamine see full prescribing information from innovator Sleep Aid Monograph, Sleep Aid MSDS, Sleep Aid FDA label

*** Taking medicines without doctor's advice can cause long-term problems.
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