Rasburicase

Rasburicase Uses, Dosage, Side Effects, Food Interaction and all others data.

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.

Drugs used to treat lympohoid leukemia, non-Hodgkin's lymphoma and acute myelogenous leukemia often lead to the accumulation of toxic plasma levels of purine metabolites (i.e. uric acid). The injection of rasburicase reduces levels of uric acid and mitigates the toxic effects of chemotherapy induced tumor lysis.

Rasburicase
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
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Interaction With other Medicine
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Trade Name	Rasburicase
Availability	Prescription only
Generic	Rasburicase
Rasburicase Other Names	Rasburicasa, Rasburicase, Urate oxidase
Related Drugs	allopurinol, sodium bicarbonate, Zyloprim, Elitek, Aloprim
Weight	1.5mg, 7.5mg,
Type	Intravenous Powder For Injection, Intravenous
Formula	C₁₅₂₁H₂₃₈₁N₄₁₇O₄₆₁S₇
Weight	34109.5 Da
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country	United States
Last Updated:	September 19, 2023 at 7:00 am

Uses

Rasburicase is a recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.

For treatment of hyperuricemia, reduces elevated plasma uric acid levels (from chemotherapy)

Rasburicase is also used to associated treatment for these conditions: Hyperuricemia