Ramoplanin

Ramoplanin Uses, Dosage, Side Effects, Food Interaction and all others data.

Ramoplanin is a novel glycolipodepsipeptide antibiotic under development for the treatment of CDAD.

Ramoplanin represents a new class of antibiotics with a novel mechanism of action that is highly effective against Staphylococci.

Ramoplanin
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Ramoplanin
Generic	Ramoplanin
Ramoplanin Other Names	Ramoplanin
Type
Formula	C₁₁₉H₁₅₄ClN₂₁O₄₀
Weight	Average: 2554.066 Monoisotopic: 2552.03504662
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

For the treatment of bacterial infections.

How Ramoplanin works

Ramoplanin is the first in a new class of antimicrobials to reach clinical trials. It is a glycolipodepsipeptide produced by the fermentation of Actinoplanes spp.. Ramoplanin blocks bacterial cell wall biosynthesis by interfering with peptidoglycan production. Ramoplanin inhibits the N-acetylglucosaminyltransferase-catalysed conversion of lipid intermediate I to lipid intermediate II, a step that occurs before the transglycosylation and transpeptidation reactions. Ramoplanin’s mechanism of action is distinct from that of glycopeptides. Unlike glycopeptides, ramoplanin does not complex with the D-Ala–D-Ala sequence of cell wall precursors.