Pranlukast Uses, Dosage, Side Effects and more
Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Pranlukast is a cysteinyl leukotriene receptor-1 antagonist.
| Trade Name | Pranlukast |
| Generic | Pranlukast |
| Pranlukast Other Names | Pranlukast |
| Type | |
| Formula | C27H23N5O4 |
| Weight | Average: 481.512 Monoisotopic: 481.175004241 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Pranlukast is a leukotriene receptor antagonist for the treatment of allergic rhinitis and asthma symptoms.
Used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists.
Pranlukast is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Asthma
How Pranlukast works
Pranlukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Pranlukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Toxicity
Side effects include headache, abdominal or stomach pain, cough, dental pain, dizziness, fever, heartburn, skin rash, stuffy nose, weakness or unusual tiredness.
