pms-Testosterone Enanthate Inj

pms-Testosterone Enanthate Inj Uses, Dosage, Side Effects, Food Interaction and all others data.

pms-Testosterone Enanthate Inj is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. pms-Testosterone Enanthate Inj antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.

pms-Testosterone Enanthate Inj was isolated from samples and also synthesized in 1935.

pms-Testosterone Enanthate Inj antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics. The duration of action of testosterone is variable from patient to patient with a half life of 10-100 minutes. The therapeutic index is wide considering the normal testosterone levels in an adult man range from 300-1000ng/dL. Counsel patients regarding the risk of secondary exposure of testosterone topical products to children.

Trade Name pms-Testosterone Enanthate Inj
Availability Prescription only
Generic Testosterone
Testosterone Other Names Testosteron, Testosterona, Testostérone, Testosterone, Testosteronum, Virosterone
Related Drugs finasteride, estradiol, tamoxifen, Premarin, norethindrone, medroxyprogesterone, megestrol, fluorouracil, AndroGel, Xyosted
Type
Formula C19H28O2
Weight Average: 288.4244
Monoisotopic: 288.20893014
Protein binding

Testosterone is 40% bound to sex hormone binding globulin, 2% unbound, and the remainder is bound to albumin and other proteins.

Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country Canada, United States
Last Updated: September 19, 2023 at 7:00 am
pms-Testosterone Enanthate Inj
pms-Testosterone Enanthate Inj

Uses

pms-Testosterone Enanthate Inj is a hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.

pms-Testosterone Enanthate Inj is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.

pms-Testosterone Enanthate Inj is also used to associated treatment for these conditions: Hypergonadotropic Hypogonadism, Hypogonadotrophic Hypogonadism, Idiopathic Hypogonadotropic Hypogonadism, Puberty, Delayed, Inoperable, metastatic Breast cancer

How pms-Testosterone Enanthate Inj works

The androgen receptor exists in the cytoplasm bound to the heat shock proteins HSP90, HSP70, and other chaperones. After binding to an androgen, the androgen receptor dissociates from HSP90 and undergoes a conformational change to slow the rate of dissociation from the androgen receptor. The androgen-receptor complex is transported into the nucleus where it binds to DNA and recruits other transcriptional regulators to form a pre-initiation complex and eventually induce expression of specific genes.

pms-Testosterone Enanthate Inj and its active metabolite dihydrotestosterone (DHT) antagonize the androgen receptor to develop masculine sex organs including the prostate, seminal vesicles, penis, and scrotum.

Antagonism of the androgen receptor is also responsible for the development of secondary sexual characteristics including facial and body hair, enlargement of the larynx, thickening of the vocal cords, and changes in muscle and fat distribution.

Toxicity

Data regarding an overdose with a topical testosterone product is not readily available. In the case of overdose with an injectable product, patients may present with a cerebrovascular event. Treat overdoses by stopping testosterone products, washing off any topical products with soap and water, and initiating symptomatic and supportive treatments.

Food Interaction

No interactions found.

pms-Testosterone Enanthate Inj Cholesterol interaction

[Major] Androgenic anabolic steroids may adversely affect serum lipids, including lowering HDL and elevating LDL levels.

These changes can be marked, particularly with the 17-alpha-alkyl derivatives (i.e., fluoxymesterone, methyltestosterone, oxandrolone, oxymetholone, and stanozolol), and may significantly impact the risk of atherosclerosis and coronary artery disease.

Patients with preexisting hyperlipoproteinemia may require closer monitoring during therapy with androgenic agents, and adjustments made accordingly in their lipid-lowering regimen.

Androgen therapy should be administered cautiously in patients with coronary artery disease or a history of ischemic heart disease.

Volume of Distribution

The volume of distribution of testosterone in elderly men is 80.36±24.51L.

Elimination Route

A single 100mg topical dose of testosterone has an AUC of 10425±5521ng*h/dL and a Cmax of 573±284ng/dL. pms-Testosterone Enanthate Inj is approximately 10% bioavailable topically.

Half Life

The half life of testosterone is highly variable, ranging from 10-100 minutes.

Clearance

The mean metabolic clearance in middle aged men is 812±64L/day.

Elimination Route

90% of an intramuscular dose is eliminated in urine, mainly as glucuronide and sulfate conjugates. 6% is eliminated in feces, mostly as unconjugated metabolites.

Innovators Monograph

You find simplified version here pms-Testosterone Enanthate Inj

FAQ

What is pms-Testosterone Enanthate Inj used for?

pms-Testosterone Enanthate Inj is used primarily to treat symptoms of sexual dysfunction in men and women and hot flashes in women. Potential benefits include improved libido, increased bone mass, and increased sense of well-being.

How safe is pms-Testosterone Enanthate Inj?

pms-Testosterone Enanthate Inj injections may be safe for many people when they follow a doctor's instructions. However, research has also linked pms-Testosterone Enanthate Inj therapy with several side effects and possible complications. Possible negative effects of pms-Testosterone Enanthate Inj therapy may include: an increased risk of cardiovascular complications.

How does pms-Testosterone Enanthate Inj work?

pms-Testosterone Enanthate Inj is a sex hormone that plays important roles in the body. In men, it's thought to regulate sex drive (libido), bone mass, fat distribution, muscle mass and strength, and the production of red blood cells and sperm. A small amount of circulating pms-Testosterone Enanthate Inj is converted to estradiol, a form of estrogen.

What are the common side effects of pms-Testosterone Enanthate Inj?

Common side effects may include:

  • breast swelling;
  • acne, increased facial or body hair growth, male-pattern baldness;
  • increased or decreased interest in sex;
  • headache, anxiety, depressed mood;
  • increased blood pressure;
  • numbness or tingly feeling;
  • abnormal liver function tests;
  • high red blood cell counts (hematocrit or hemoglobin);
  • increased PSA (prostate-specific antigen); or
  • pain, bruising, bleeding, redness, or a hard lump where the medicine was injected.

Is pms-Testosterone Enanthate Inj safe during pregnancy?

If you are pregnant, avoid starting pms-Testosterone Enanthate Inj, as it will harm the developing fetus.

Is pms-Testosterone Enanthate Inj safe during breastfeeding?

pms-Testosterone Enanthate Inj delivered by sublingual drops, vaginal cream, and pellet implant was absorbed but not measurably excreted into breast milk. pms-Testosterone Enanthate Inj, delivered by a 100-mg subcutaneous pellet implant, was effective in relieving symptoms of pms-Testosterone Enanthate Inj deficiency and therapy is safe for the breast-fed infant.

Can I drink alcohol with pms-Testosterone Enanthate Inj?

Many doctors recommend limiting or quitting alcohol while taking pms-Testosterone Enanthate Inj. More than 90 percent of men with advanced liver disease also have low pms-Testosterone Enanthate Inj. Continuing to drink may worsen liver damage, which will lead to more health problems and further impaired pms-Testosterone Enanthate Inj production.

Does pms-Testosterone Enanthate Inj make I last longer?

With the higher levels of energy and improved muscle mass pms-Testosterone Enanthate Inj replacement therapy brings, you'll also have more stamina and strength to last longer during sex.

How long after taking pms-Testosterone Enanthate Inj do I feel effects?

Effects on sexual interest appear after 3 weeks plateauing at 6 weeks, with no further increments expected beyond. Changes in erections/ejaculations may require up to 6 months. Effects on quality of life manifest within 3–4 weeks, but maximum benefits take longer.

When is the best time of day to inject pms-Testosterone Enanthate Inj?

Traditionally, it's the morning. It's not scientifically necessary to inject pms-Testosterone Enanthate Inj in the morning, though our pms-Testosterone Enanthate Inj is at the highest levels in the morning.

How long does pms-Testosterone Enanthate Inj take to work after injection?

Most individuals will start to notice significant changes within 4 to 6 weeks of beginning treatment with pms-Testosterone Enanthate Inj injections, but some changes may actually be felt and seen much earlier.

How long does a pms-Testosterone Enanthate Inj injection last?

Injections of pms-Testosterone Enanthate Inj will last approximately 15-17 days and after that there will be a dramatic drop. The 14 day treatment schedule keeps that dramatic drop from occurring.

Can I take pms-Testosterone Enanthate Inj for a long time?

Indefinitely. TRT does not cure low pms-Testosterone Enanthate Inj, so your symptoms may return if you stop taking it.

Is pms-Testosterone Enanthate Inj harmful?

pms-Testosterone Enanthate Inj can increase your risk of heart attack, stroke, or death. You may need to stop using pms-Testosterone Enanthate Inj or start taking blood pressure medication.

Who should not take pms-Testosterone Enanthate Inj?

Men who have prostate cancer or breast cancer should not take pms-Testosterone Enanthate Inj replacement therapy. Nor should men who have severe urinary tract problems, untreated severe sleep apnea or uncontrolled heart failure.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your pms-Testosterone Enanthate Inj injection.

What happen if I take too much pms-Testosterone Enanthate Inj?

If you have used too much testosterone, stopping the medicine may caused unpleasant withdrawal symptoms, such as depression, tiredness, irritability, loss of appetite, sleep problems, or decreased libido.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

Will pms-Testosterone Enanthate Inj affect my fertility?

pms-Testosterone Enanthate Inj treatment decreases sperm production by decreasing levels of another hormone, follicelstimulating hormone (FSH), which is important for stimulating sperm production. In most cases, the infertility caused by testosterone treatment is reversible.

Can pms-Testosterone Enanthate Inj affects my heart ?

Some studies have reported that pms-Testosterone Enanthate Inj therapy might increase the risk of a heart attack in men age 65 and older, as well as in younger men who have a history of heart disease.

Can pms-Testosterone Enanthate Inj affect my kidneys?

Genetically predicted pms-Testosterone Enanthate Inj was associated with CKD and worse kidney function in men, whilst not affected by kidney function. Identifying drivers of pms-Testosterone Enanthate Inj and the underlying pathways could provide new insights into CKD prevention and treatment.

Can pms-Testosterone Enanthate Inj affects my liver?

pms-Testosterone Enanthate Inj may adversely affect liver function.

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