Perflutren

Perflutren Uses, Dosage, Side Effects, Food Interaction and all others data.

Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.

Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. It provide contrast enhancement of the endocardial borders during echocardiography. The perflutren lipid microspheres exhibit lower acoustic impedance than blood and enhance the intrinsic backscatter of blood.

Trade Name Perflutren
Availability Prescription only
Generic Perflutren
Perflutren Other Names Freon 218, Octafluoropropane, Octafluorpropan, Oktafluorpropan, Perfluoropropane, Perflutren, Perflutreno
Related Drugs Definity, Optison
Weight (lipidmicrospheres, protein + typeamicrospheres
Type Intravenous suspension,)
Formula C3F8
Weight Average: 188.0193
Monoisotopic: 187.98722564
Groups Approved
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Perflutren
Perflutren

Uses

Perflutren is a diagnostic medication to improve contrast during echocardiograms.

Used as an ultrasound contrast imaging in cardiology and radiology.

How Perflutren works

Perflutren is comprised of gas-filled microspheres that are injected or infused into the body. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.

Toxicity

There is new temporal evidence that perflutren may be associated with new-onset seizure activity following perflutren microbubble contrast injection during dobutamine-atropine stress echocardiography. [PMID: 23432576]

Food Interaction

No interactions found.

Half Life

The mean half-life of OFP in blood 1.9 minutes

Innovators Monograph

You find simplified version here Perflutren

*** Taking medicines without doctor's advice can cause long-term problems.
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