Pedeamin 10 mg/5 ml Syrup Uses, Dosage, Side Effects and more

Attribute	Details
Trade Name	Pedeamin 10 mg/5 ml Syrup
Generic	Diphenhydramine Hydrochloride
Weight	10 mg/5 ml
Type	Syrup
Therapeutic Class	Sedating Anti-histamine
Manufacturer	Beximco Pharmaceuticals Ltd.
Available Country	Bangladesh
Last Updated:	January 7, 2025 at 1:49 am

Uses

Diphenhydramine is indicated for the treatment of followings: Seasonal, perennial, vasomotor rhinitis Urticaria, angioneurotic oedema, anaphylaxis Pruiritic conditions Premedication for emesis and motion sickness Miscellaneous like meniere's disease and parkinsonism

Dosage

Adult- Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night. Children- 1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day

How Long Does It Take to Work?

How Long Does It Take to Work? see here Pedeamin 10 mg/5 ml Syrup

Side Effects

Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort. See simplified version Pedeamin 10 mg/5 ml Syrup also Pedeamin 10 mg/5 ml Syrup in bangla

Precaution

Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.

Interaction

Diphenhydramine administration significantly reduces the absorption of the antituberculous agent para-aminosalicyclic acid (PAS) from the gastrointestinal tract. CNS depressants may potentiate the sedative action of Diphenhydramine. Anticholinergic drugs may potentiate Diphenhydramine’s anticholinergic side effects.

Pregnancy & Breastfeeding use

Category B: There are no adequate and well controlled studies in pregnant women using diphenhydramine hydrochloride. Therefore, diphenhydramine hydrochloride should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of diphenhydramine hydrochloride in lactating mother is not recommended.

Contraindication

Known hypersensitivity to Pedeamin 10 mg/5 ml Syrup, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.

Acute Overdose

Symptoms: Impaired consciousness; psychosis, seizures, antimuscarinic symptoms (e.g. mydriasis, tachycardia, tachyarrhythmias), resp failure, rhabdomyolysis; acute delirium with visual and auditory hallucination (topical). Management: Supportive and symptomatic treatment. Convulsions and marked CNS stimulation may be treated with IV diazepam.