Novamoxin Reduced Sugar

Novamoxin Reduced Sugar Uses, Dosage, Side Effects, Food Interaction and all others data.

Amoxycillin is a semi-synthetic antibiotic, an analog of ampicillin, with a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. Amoxycillin is bactericidal against susceptible organisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell wall mucopeptides.

Novamoxin Reduced Sugar competitively inhibit penicillin binding proteins, leading to upregulation of autolytic enzymes and inhibition of cell wall synthesis. Novamoxin Reduced Sugar has a long duration of action as it is usually given twice daily. Novamoxin Reduced Sugar has a wide therapeutic range as mild overdoses are not associated with significant toxicity. Patients should be counselled regarding the risk of anaphylaxis, Clostridium difficile infections, and bacterial resistance.

Trade Name Novamoxin Reduced Sugar
Availability Prescription only
Generic Amoxicillin
Amoxicillin Other Names Amox, Amoxicilina, Amoxicillin, Amoxicilline, Amoxicillinum, Amoxycillin, p-Hydroxyampicillin
Related Drugs prednisone, omeprazole, albuterol, pantoprazole, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin, clindamycin
Type Oral
Formula C16H19N3O5S
Weight Average: 365.404
Monoisotopic: 365.104541423
Protein binding

Amoxicillin is 17% protein bound in serum.

Groups Approved, Vet approved
Therapeutic Class Broad spectrum penicillins
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Novamoxin Reduced Sugar
Novamoxin Reduced Sugar

Uses

Novamoxin Reduced Sugar is used for the treatment of the following bacterial infections when caused by susceptible organisms:

  • Respiratory tract, ENT infections: Acute and chronic bronchitis, pneumonia, otitis media, sinusitis, tonsillitis, pharyngitis & laryngitis, lobar & bronchopneumonia, chronic bronchial sepsis.
  • Urinary tract infections: Pyelonephritis, cystitis and urethritis.
  • Obstetric & gynaecological infections: Bacteriuria in pregnancy, septic abortion, intra-abdominal sepsis and puerperal sepsis.
  • Gastro-intestinal infections: Typhoid and paratyphoid.
  • Skin & soft tissue infections: Cellulitis, infected wounds and abscesses.
  • Generalized infections: Septicemia, bacterial endocarditis, meningitis, peritonitis and osteomyelitis.
  • Venereal infections: Gonorrhea and syphilis. Novamoxin Reduced Sugar may also be used as prophylactic cover for patients at risk of developing endocarditis when undergoing dental surgery.

Novamoxin Reduced Sugar is also used to associated treatment for these conditions: Acute Bacterial Sinusitis (ABS), Acute Otitis Media, Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary infections, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections

How Novamoxin Reduced Sugar works

Novamoxin Reduced Sugar competitively inhibits penicillin-binding protein 1 and other high molecular weight penicillin binding proteins. Penicillin bind proteins are responsible for glycosyltransferase and transpeptidase reactions that lead to cross-linking of D-alanine and D-aspartic acid in bacterial cell walls. Without the action of penicillin binding proteins, bacteria upregulate autolytic enzymes and are unable to build and repair the cell wall, leading to bacteriocidal action.

Dosage

Novamoxin Reduced Sugar dosage

Ear/Nose/ThroatInfection (Mild to Moderate):

  • Adult:500 mg every 12 hours or 250 mg every 8 hours
  • Children:25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours

Ear/Nose/ThroatInfection (Severe):

  • Adult: 875 mg every 12 hours or 500 mg every 8 hours
  • Children: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours

Lower respiratory tractInfection (Mild/ Moderate/Severe):

  • Adult: 875 mg every 12 hours or 500 mg every 8 hours
  • Children: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours

Skin/skin structureInfection (Mild/Moderate):

  • Adult: 500 mg every 12 hours or 250 mg every 8 hours
  • Children: 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours

Skin/skin structureInfection (Severe):

  • Adult: 875 mg every 12 hours or 500 mg every 8 hours
  • Children: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours

Genitourinary tractInfection (Mild/ Moderate):

  • Adult: 500 mg every 12 hours or 250 mg every 8 hours
  • Children: 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours

Genitourinary tractInfection (Severe):

  • Adult: 875 mg every 12 hours or 500 mg every 8 hours
  • Children: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours

Gonorrhea, Acute, uncomplicated ano-genital, and urethral infections in males and females:

  • Adult: 3 g as single oral dose
  • Prepubertal children: 50 mg/Kg/Amoxycillin, combined with 25 mg/kg Probenecid as a single dose. Since Probenecid is contraindicated in children under 2 years, do not use this regimen in these cases.

Suspension: Shake the bottle well before adding water. Then add 12 tea spoonful (60 ml) of boiled and cooled water to the bottle and shake well to make 100 ml suspension.

Amoxycillin 500 mg Injection:

  • Intramuscular : Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial.
  • Intravenous : Dissolve Amoxycillin 500 mg injection in 10 ml water for injection.

Side Effects

Side effects are mild, rare and infrequent. As with other penicillins, it may induce diarrhea, indigestion or skin rashes that usually stop during treatment and rarely calls for discontinuation of therapy.

Toxicity

Patients experiencing an overdose may present with hematuria, oliguria, abdominal pain, acute renal failure, vomiting, diarrhea, rash, hyperactivity, and drowsiness. Treat overdose with symptomatic and supportive treatment, which may include emesis or hemodialysis.

Precaution

In renal impairment, the excretion of antibiotic will be delayed and depending on the degree of impairment it may be necessary to reduce the total daily dose.

Interaction

The simultaneous use of Novamoxin Reduced Sugar and an oral contraceptive might cause breakthrough bleeding or pregnancy on rare occasions. Concurrent administration of probenecid delays the excretion of Novamoxin Reduced Sugar.

Food Interaction

  • Take with food.

Novamoxin Reduced Sugar Disease Interaction

Major: colitisModerate: mononucleosis, diabetes, renal dysfunction, hemodialysis

Volume of Distribution

The central volume of distribution of amoxicillin is 27.7L.

Elimination Route

Novamoxin Reduced Sugar is approximately 60% bioavailable. A 250mg dose of oral amoxicillin reaches a Cmax 3.93±1.13mg/L with a Tmax 1.31±0.33h and an AUC of 27.29±4.72mg*h/L. A 875mg dose of oral amoxicillin reaches a Cmax 11.21±3.42mg/L with a Tmax 1.52±0.40h and an AUC of 55.04±12.68mg*h/L.

Half Life

The half life of amoxicillin is 61.3 minutes.

Clearance

The mean clearance of amoxicillin is 21.3L/h.

Elimination Route

125mg to 1g doses of amoxicillin are 70-78% eliminated in the urine after 6 hours.

Pregnancy & Breastfeeding use

Because of its lack of teratogenicity, Novamoxin Reduced Sugar can beused safely throughout pregnancy at the normal adult dose. The small amount of Novamoxin Reduced Sugar secreted in maternal milk rarely causes problem in the infant. It can therefore be used safely during lactation in most instances.

Contraindication

Novamoxin Reduced Sugar is contraindicated for patients hypersensitive to penicillin, infectious mononucleosis, neonatal period or babies born of mothers hypersensitive to penicillin

Acute Overdose

If encountered, gastro-intestinal symptoms and disturbance of the fluid and electrolyte balance may be evident. They may be treated symptomatically and supportive with attention to the water/ electrolyte balance. In the absence of an adequate fluid intake and urinary output, crystalluria is a possibility and the antibiotic may be removed from the circulation by haemodialysis. Oral administration can cause gastro intestinal symptoms such as transient diarrhoea, nausea and colic which are dose related and a result of local irritation not toxicity.

Storage Condition

Store in a cool & dry place protected from light. Novamoxin Reduced Sugar suspension and drops should be freshly prepared, stored in a cool dry place preferably in a refrigerator. Reconstituted suspension and drops should be used within 5 days if kept at room temperature or within 7 days if kept in a refrigerator.

Innovators Monograph

You find simplified version here Novamoxin Reduced Sugar

Novamoxin Reduced Sugar contains Amoxicillin see full prescribing information from innovator Novamoxin Reduced Sugar Monograph, Novamoxin Reduced Sugar MSDS, Novamoxin Reduced Sugar FDA label

FAQ

What is Novamoxin Reduced Sugar used for?

Novamoxin Reduced Sugar is used to treat bacterial infections, such as chest infectionsand dental abscesses.

How safe is Novamoxin Reduced Sugar?

Novamoxin Reduced Sugar is a safe and affordable antibiotic; however, it is not the right antibiotic for all infections. It is important not to share your antibiotics with anyone. An antibiotic is prescribed specifically for you and your particular type of bacterial infection.

How does Novamoxin Reduced Sugar work?

Novamoxin Reduced Sugar work by binding proteins and inhibiting certain processes in bacterial cells.

What are the common side effects of Novamoxin Reduced Sugar?

The most common side effects of Novamoxin Reduced Sugar are feeling sick and diarrhoea. Liquid Novamoxin Reduced Sugar can stain your teeth. This does not last and is removed by brushing. You can drink alcohol while taking Novamoxin Reduced Sugar.

Is Novamoxin Reduced Sugar safe during pregnancy?

Novamoxin Reduced Sugar is in the penicillin family of antibiotics. Some antibiotics are safe to take during pregnancy, while others are not.Novamoxin Reduced Sugar is considered a pregnancy category B drug by the U.S. Food and Drug Administration. That means it’s considered safe to take while pregnant. it's considered safe to take while pregnant.

Is Novamoxin Reduced Sugar safe during breastfeeding?

Novamoxin Reduced Sugar is used to treat infections in babies and it can be used by women who are breastfeeding.Novamoxin Reduced Sugar passes into breast milk and although this is unlikely to have any harmful effects on a nursing infant, it could theoretically affect the natural bacteria found in the baby's mouth or gut.

Can I drink alcohol with Novamoxin Reduced Sugar?

Yes, you can drink alcohol while taking the antibiotic Novamoxin Reduced Sugar. The alcohol will not stop Novamoxin Reduced Sugar from working. However, many health professionals will recommend you avoid alcohol to give your body the best chance possible to fight the infection.

Can I drive after taking Novamoxin Reduced Sugar ?

Novamoxin Reduced Sugar can have side effects and the symptoms may make you unfit to drive. Do not drive or operate machinery unless you are feeling well.

When should be taken of Novamoxin Reduced Sugar?

Novamoxin Reduced Sugar is usually taken every 12 hours or every 8 hours with or without food. The length of your treatment depends on the type of infection that you have. Take Novamoxin Reduced Sugar at around the same times every day.

Should Novamoxin Reduced Sugar be taken on an empty stomach?

Take this medicine by mouth with a glass of water. Follow the directions on your prescription label.You can take it with or without food. If it upsets your stomach, take it with food.

Can I take Novamoxin Reduced Sugar once a day?

Novamoxin Reduced Sugar is ideal for once-daily dosing due to its low cost.

How long should Novamoxin Reduced Sugar take to work?

Novamoxin Reduced Sugar begins to work quickly after a patient takes it, and it reaches peak blood concentrations in about one or two hours, according to the drug's label. However, improvement in symptoms will take longer.

How long do Novamoxin Reduced Sugar stay in my system?

After taking an oral dose of Novamoxin Reduced Sugar, 60% of it will be out of your system in 6 to 8 hours.

Can I take Novamoxin Reduced Sugar for a long time?

A person may take antibiotics for a long time for severe or continued infections, such as osteomyelitis. Doing so puts them at higher risk of long-term complications , including crystalluria, hemolytic anemia, and nephritis.

How long can I take Novamoxin Reduced Sugar?

Novamoxin Reduced Sugar also depends on the type of infection you're treating. Most antibiotics should be taken for 7 to 14 days.

How should not take Novamoxin Reduced Sugar?

You should not use Novamoxin Reduced Sugar if you are allergic to any penicillin antibiotic, such as Novamoxin Reduced Sugar.

What happens if I miss a dose of Novamoxin Reduced Sugar?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

Can Novamoxin Reduced Sugar effects my fertility?

Antibiotics affect both the quantity and quality of sperm. They may reduce the number of sperm a man produces, and make the sperm he does produce swim more slowly.

What happen if I overdose on Novamoxin Reduced Sugar?

Antibiotic overdoses are rarely dangerous, but stomach upset and diarrhea may occur. Taking the wrong antibiotic is a problem if someone is allergic to the drug.

Does Novamoxin Reduced Sugar make sleepy?

If you're taking prescription Novamoxin Reduced Sugar, you may feel tired and fatigued.

Can I take Novamoxin Reduced Sugar before bed?

It is generally not a good idea to take these medications right before bedtime.

Do Novamoxin Reduced Sugar weaken my immune system?

Very rarely, antibiotic treatment will cause a drop in the blood count, including the numbers of white cells that fight infection. This corrects itself when the treatment is stopped.

Do Novamoxin Reduced Sugar affect the liver?

Novamoxin Reduced Sugar are a common cause of drug-induced liver injury.

*** Taking medicines without doctor's advice can cause long-term problems.
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