Norcisapride

Norcisapride Uses, Dosage, Side Effects, Food Interaction and all others data.

Table Of contents

• Norcisapride
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Norcisapride
Generic	Ticalopride
Ticalopride Other Names	Norcisapride, Ticalopride
Type
Formula	C14H20ClN3O3
Weight	Average: 313.78 Monoisotopic: 313.119319228
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Investigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.

How Norcisapride works

Norcisapride is an isomer of the active metabolite of cisapride. Cisapride acts through the stimulation of the serotonin 5-HT4 receptors which increases acetylcholine release in the enteric nervous system (specifically the myenteric plexus). This results in increased tone and amplitude of gastric (especially antral) contractions, relaxation of the pyloric sphincter and the duodenal bulb, and increased peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit.

Innovators Monograph

You find simplified version here Norcisapride