Mitiglinide

Mitiglinide Uses, Dosage, Side Effects, Food Interaction and all others data.

Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.

Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs. It is approved for use in Japan but has not yet gained FDA approval.

Table Of contents

• Mitiglinide
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Mitiglinide
Generic	Mitiglinide
Mitiglinide Other Names	Mitiglinide
Type
Formula	C19H25NO3
Weight	Average: 315.413 Monoisotopic: 315.183443669
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

For the treatment of type 2 diabetes.

Mitiglinide is also used to associated treatment for these conditions: Post-prandial Blood Glucose, Type 2 Diabetes Mellitus

How Mitiglinide works

Mitiglinide is thought to stimulate insulin secretion by binding to and blocking ATP-sensitive K(+) (K(ATP)) channels (Kir6.2/SUR1 complex, KATP channels) in pancreatic beta-cells. Closure of potassium channels causes depolarization which stimulates calcium influx through voltage-gated calcium channels. High intracellular calcium subsequently triggers the exocytosis of insulin granules.

Innovators Monograph

You find simplified version here Mitiglinide