Мебеверин гранулы Uses, Dosage, Side Effects and more
Мебеверин гранулы is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestine (gut). It is particularly useful in treating Irritable Bowel Syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping to restore the normal movement of the gut.
| Attribute | Details |
|---|---|
| Trade Name | Мебеверин гранулы |
| Generic | Mebeverine |
| Mebeverine Other Names | Mebeverina, Mebeverine, Mebeverinum |
| Type | |
| Formula | C25H35NO5 |
| Weight | Average: 429.557 Monoisotopic: 429.251523231 |
| Groups | Approved, Investigational |
| Therapeutic Class | Anticholinergics |
| Manufacturer | |
| Available Country | Russia |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
For the symptomatic treatment of Irritable Bowel Syndrome (IBS) and other conditions include:
- Chronic irritable colon
- Spastic constipation
- Mucous colitis
- Colicky abdominal pain
- Persistent non-specific diarrhea
Мебеверин гранулы is also used to associated treatment for these conditions: Abdominal Pain, Abdominal Spasms, Abnormal Bowel Movement Such as Constipation, Diarrhea, Abdominal Pain, Irritable Bowel Syndrome (IBS), Bowel discomfort
Dosage
135 mg tid, may reduce gradually after several wk when the desired effect has been obtained; 100 mg tid has also been used. As modified-release cap: 200 mg bid.
Мебеверин гранулы is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced.
Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.
Side Effects
Generally Мебеверин гранулы is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.
Precaution
Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised. Мебеверин гранулы does not excrete in the breast milk after administering the therapeutic dose.
Special Warning
Use in children: Мебеверин гранулы is not recommended in children under 10 years.
Acute Overdose
Symptoms: CNS excitability
Management: Symptomatic and supportive treatment. Gastric lavage may be considered in case of multiple intoxication or if discovered w/in approx 1 hr.
Storage Condition
Store below 30° C.
Innovators Monograph
Мебеверин гранулы contains Mebeverine see full prescribing information from innovator Monograph, MSDS, FDA label
FAQ
What is Мебеверин гранулы used for?
Мебеверин гранулы helps with muscle spasms. It can be used to ease painful stomach cramps if you have irritable bowel syndrome (IBS) or other conditions.
How safe is Мебеверин гранулы?
Мебеверин гранулы is generally safe and you're unlikely to have side effects. Some people may get an itchy rash (hives).
How does Мебеверин гранулы work?
Мебеверин гранулы works by relaxing the muscles in your intestine. This relieves the cramps and pain that can be caused by IBS or other conditions.
What are the common side effects of Мебеверин гранулы?
The common side effects of Мебеверин гранулы are:
- Nausea.
- Vomiting.
- Rash.
- Headache.
- Heartburn.
- Indigestion.
- Constipation.
- Dizziness.
Is Мебеверин гранулы safe during pregnancy?
Мебеверин гранулы are not recommended during pregnancy.
Is Мебеверин гранулы safe during breastfeeding?
It is usually safe to breastfeed while taking Мебеверин гранулы. Some of the medicine may pass into your breast milk. However, this is in small amounts and unlikely to harm your baby.
Can I drink alcohol with Мебеверин гранулы?
Yes, you can drink alcohol with Мебеверин гранулы.
When should be best taken of Мебеверин гранулы?
It's best to take your Мебеверин гранулы 20 minutes before a meal.
How often can I take Мебеверин гранулы?
The recommended dose is one tablet three times a day. Do not take more than three tablets per day.
Can I Мебеверин гранулы take on an empty stomach?
Мебеверин гранулы should take on an empty stomach. If you take it twice a day, take it before breakfast and dinner. If you take it 3 times a day, take it before breakfast, lunch and dinner.
How long does Мебеверин гранулы take to work?
Мебеверин гранулы starts to work after 1 hour. You should feel better 1 to 3 hours after taking it.
What is the half life of Мебеверин гранулы?
The steady state elimination half-life of DMAC is 2.45 h.
Does Мебеверин гранулы raise blood pressure?
Мебеверин гранулы also significantly reduced heart rate and arterial blood pressure.
Can I take Мебеверин гранулы for a long time?
You will usually only take Мебеверин гранулы if you are having a flare-up of your IBS symptoms.
Who should not take Мебеверин гранулы?
The recommended dose is one tablet three times a day. Do not take more than three tablets per day. The number of tablets you take may be lowered if your symptoms improve. Children and adolescents: Мебеверин гранулы is not recommended for use in children and adolescents below 18 years of age.
What happen If I missed Мебеверин гранулы?
If you miss a dose of Мебеверин гранулы, skip the missed dose and take the next one as usual. Do not take a double dose to make up for a missed dose. If you forget doses often, it may help to set an alarm to remind you.
What happens if I take too much Мебеверин гранулы?
If you take too much Мебеверин гранулы by accident, it is unlikely to harm you. Speak to a pharmacist or doctor if you're worried.
Can I just stop taking Мебеверин гранулы?
You can stop taking Мебеверин гранулы when you feel better. This may take up to 2 weeks. If you do not get better within 2 weeks of taking Мебеверин гранулы, or get worse at any time, talk to a doctor.
Does Мебеверин гранулы raise blood pressure?
Мебеверин гранулы also significantly reduced heart rate and arterial blood pressure.
Does Мебеверин гранулы cause tachycardia?
Transient bradycardia followed by tachycardia.
