Magaldrate

Magaldrate Uses, Dosage, Side Effects, Food Interaction and all others data.

Magaldrate is a hydroxymagnesium aluminate complex that is converted rapidly in gastric acid to Mg(OH)2 and Al(OH)3, which are absorbed poorly and thus provide a sustained antacid effect

Trade Name Magaldrate
Availability Discontinued
Generic Magaldrate
Magaldrate Other Names Aluminium magnesium hydroxide sulfate hydrate, Aluminum magnesium hydroxide sulfate hydrate, Aluminum magnesium hydroxide sulphate hydrate, Hydrate magnesium aluminate activated sulfate, Magaldrate, Magaldrato, Magaldratum, Magnesium aluminate hydrate, Monalium hydrate
Related Drugs omeprazole, famotidine, Pepcid, Prilosec, ranitidine, calcium carbonate
Type
Formula Al5H33Mg10O40S2
Weight Average: 1115.3
Monoisotopic: 1111.7570627
Groups Approved, Withdrawn
Therapeutic Class Antacids, Anti-dyspeptic/Carminatives
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Magaldrate
Magaldrate

Uses

Magaldrate is used to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux, hiatal hernia and flatulence. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis. Magaldrate may be given to children if necessary.

Magaldrate is also used to associated treatment for these conditions: Acid indigestion, Aspiration, Bloating, Calcinosis, Dyspepsia, Gastroesophageal Reflux, Gastrointestinal Bleeding, Heartburn, Hyperacidity, Hyperparathyroidism, Kidney Stones, Peptic Ulcer, Stress Ulcers

Dosage

Magaldrate dosage

Tablet: 1-3 tablets, after meals and at bed time or as directed by the physician.

Syrup: 2 to 3 teaspoonful, 3 or 4 times daily, half to one hour after or before meal and at bedtime

Side Effects

Constipation and diarrhea may occur.

Food Interaction

  • Avoid alcohol.

Elimination Route

Aluminium oxide: absorbed Al ions are eliminated in the urine (0.1-0.5 mg of Al in aluminium-containing antacid is absorbed from standard daily doses of antacid) while insoluble or poorly absorbed Al salts in the intestines are excreted through the feces.

Magnesium oxide: absorbed Mg ions (up to 30%) are eliminated in the urine, unabsorbed is excreted in the feces.

Pregnancy & Breastfeeding use

Pregnant women: Magaldrate may be used in pregnancy if indicated however one should avoid excessive dosage.

Lactating mother: Magaldrate may pass into breast milk but has not been reported to cause problem in nursing babies.

Contraindication

Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal function

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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