Intrinsic factor

Intrinsic factor Uses, Dosage, Side Effects, Food Interaction and all others data.

Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. When vitamin B12 is provided in combination with intrinsic factor, intrinsic factor reduces protease degradation and increases absorption of Vitamin B12.

Intrinsic factor is not currently available in any FDA or Health Canada approved products. However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias responsive to oral iron therapy.

Trade Name Intrinsic factor
Generic Gastric intrinsic factor
Gastric intrinsic factor Other Names Intrinsic factor
Type
Groups Approved, Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Intrinsic factor
Intrinsic factor

Uses

Intrinsic factor is not currently available in any FDA or Health Canada approved products. However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias responsive to oral iron therapy.

How Intrinsic factor works

Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. When vitamin B12 is provided in combination with intrinsic factor, intrinsic factor reduces protease degradation and increases absorption of Vitamin B12.

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here Intrinsic factor

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