Hyoscine Hydrobromide

Hyoscine Hydrobromide Uses, Dosage, Side Effects, Food Interaction and all others data.

Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.

Trade Name Hyoscine Hydrobromide
Generic Hyoscine Hydrobromide
Type
Therapeutic Class Anti-emetic drugs
Manufacturer Wockhardt UK Ltd
Available Country United Kingdom
Last Updated: September 19, 2023 at 7:00 am
Hyoscine Hydrobromide
Hyoscine Hydrobromide

Uses

Motion sickness

Dosage

Hyoscine Hydrobromide dosage

Adult & Children over 12 years: 300 mcg 30 mins before journey, then 300 mcg 6 hrly if needed. Max: 3 doses in 24 hr.

Children 4-12 years: 1 tablet (150 mcg) 30 mins before journey. Maximum 2 tablet in 24 hours.

Children 3-4 years: ½ tab 30 mins before journey. Maximum 1 tablet in 24 hours.

Side Effects

Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOR local irritation, photophobia, vascular and respiratory congestion.

Precaution

Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation

Interaction

Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine).

Pregnancy & Breastfeeding use

Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Contraindication

Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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