HLA-matched Virus Specific T Cells Uses, Dosage, Side Effects and more
HLA-matched Virus Specific T Cellss (VSTs) are a target therapy that are generated for specific viral antigens. These products are generated from virus-naive or virus-experienced autologous or allogenic sources. Antigens identified as an immune target are presented by antigen-presenting cells (APCs) to T-cells along with other molecules that stimulate their growth and activation. These T-cells are then isolated from the donor and expanded in a culture to generate more VSTs. In some cases, the cells are created from blood samples of patients who have recovered from viral infections.
| Attribute | Details |
|---|---|
| Trade Name | HLA-matched Virus Specific T Cells |
| Generic | Virus Specific T-Cell |
| Virus Specific T-Cell Other Names | HLA-matched Virus Specific T Cells, Partially HLA-matched Virus Specific T Cell, Viral Specific T-lymphocytes, VST |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
How HLA-matched Virus Specific T Cells works
Administration of VSTs can provide physiological protection against specific infections, especially for patients who are immunocompromised and depleted of T-cells. VSTs are used as an immunotherapy against many infections, including Epstein-Barr virus, adenovirus, BK virus, and human herpesvirus type 6. This type of treatment is also being investigated as a therapy against SARS-Cov-2.
