Histalex

Histalex Uses, Dosage, Side Effects, Food Interaction and all others data.

Histalex is an ethylenediamine derivative antihistamine with antimuscarinic and sedative properties.

Trade Name Histalex
Generic Mebhydrolin
Mebhydrolin Other Names Mebhydrolin
Weight 50mg, 4mg, 2mg/5ml
Type Tablet, Syrup
Formula C19H20N2
Weight Average: 276.383
Monoisotopic: 276.162648652
Groups Experimental
Therapeutic Class Sedating Anti-histamine
Manufacturer Pharmedic (pvt) Ltd,, Acme Laboratories Limited
Available Country Pakistan, Bangladesh
Last Updated: September 19, 2023 at 7:00 am
Histalex
Histalex

Uses

Allergic disease or symptoms such as urticaria, pruritus of various origin, eczema, itching, drug rash, insect bites, allergic conjunctivitis, dermatitis of nutritional origin, hay fever, vasomotor rhinitis, allergic asthma.

Histalex is also used to associated treatment for these conditions: Allergies

Dosage

Histalex dosage

Adult: 100-300 mg/day or 2-6 tablets daily.

Child:

  • 2-5 year: 50-150 mg/day or 1-3 tablets daily;
  • 5-10 year: 100-200 mg/day or 2-4 tablets daily;
  • >10 year: 100-300 mg/day or 2-6 tablets daily.

Treatment should be given in several single doses daily. Histalex may be swallowed during or shortly after meals. For children, the tablet may be crushed and mixed with food.

Side Effects

Lassitude, dizziness, hypotension, muscular weakness, nausea, vomiting, diarrhoea or constipation, epigastric pain, headache, blurred vision, tinnitus, depression, nightmares, anorexia, dryness of the mouth, tightness of the chest, tingling, sedation, drowsiness etc. may occur.

Precaution

Closed-angle glaucoma; urinary retention, prostatic hyperplasia or pyloroduodenal obstruction; epilepsy. Elderly. Pregnancy. May impair ability to drive or operate machinery

Interaction

Enhanced sedation with alcohol or other CNS depressants. Additive antimuscarinic effects with MAOIs, atropine, TCAs. May mask warning symptoms caused by ototoxic agents e.g. aminoglycoside antibiotics.

Pregnancy & Breastfeeding use

Safety in pregnancy and lactation has not been established.

Contraindication

Hypersensitivity to any of the ingredients of Histalex tablet or to mebhydrolin, prostatic hypertrophy, narrow-angle glaucoma, first trimester of pregnancy

Special Warning

Safety in pregnancy and lactation has not been established.

Storage Condition

Store below 25° C.

Innovators Monograph

You find simplified version here Histalex

*** Taking medicines without doctor's advice can cause long-term problems.
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