Flunisolidum

Flunisolidum Uses, Dosage, Side Effects, Food Interaction and all others data.

Flunisolidum (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.

Flunisolidum is a synthetic corticosteroid. It is administered either as an oral metered-dose inhaler for the treatment of asthma or as a nasal spray for treating allergic rhinitis. Corticosteroids are naturally occurring hormones that prevent or suppress inflammation and immune responses. When given as an intranasal spray, flunisolide reduces watery nasal discharge (rhinorrhea), nasal congestion, postnasal drip, sneezing, and itching oat the back of the throat that are common allergic symptoms.

Trade Name Flunisolidum
Availability Discontinued
Generic Flunisolide
Flunisolide Other Names Flunisolida, Flunisolide, Flunisolidum
Related Drugs Trelegy Ellipta, prednisone, Breo Ellipta, Xopenex, Dulera, Atrovent, Fasenra
Type
Formula C24H31FO6
Weight Average: 434.4977
Monoisotopic: 434.210466929
Protein binding

Approximately 40% after oral inhalation

Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Flunisolidum
Flunisolidum

Uses

Flunisolidum is an inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.

For the maintenance treatment of asthma as a prophylactic therapy.

Flunisolidum is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Asthma

How Flunisolidum works

Flunisolidum is a glucocorticoid receptor agonist. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Flunisolidum binds to plasma transcortin, and it becomes active when it is not bound to transcortin.

Food Interaction

No interactions found.

Elimination Route

Absorbed rapidly

Half Life

1.8 hours

Innovators Monograph

You find simplified version here Flunisolidum

*** Taking medicines without doctor's advice can cause long-term problems.
Share