Fensuximida

Fensuximida Uses, Dosage, Side Effects, Food Interaction and all others data.

Fensuximida is a member of the succinimide class with anticonvulsant properties. It suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in petit mal seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.

Fensuximida suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.

Trade Name Fensuximida
Availability Discontinued
Generic Phensuximide
Phensuximide Other Names Fensuccimide, Fensuximida, Phensuximide, Phensuximidum
Type
Formula C11H11NO2
Weight Average: 189.2105
Monoisotopic: 189.078978601
Protein binding

21%

Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Fensuximida
Fensuximida

Uses

For the treatment of epilepsy.

How Fensuximida works

Fensuximida's mechanism of action not understood, but may act in inhibitory neuronal systems that are important in the generation of the three per second rhythm. It's effects may be related to its ability to inhibit depolarization-induced accumulation of cyclic AMP and cyclic GMP in brain tissue.

Food Interaction

[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.

Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.

Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Elimination Route

Rapid and complete.

Innovators Monograph

You find simplified version here Fensuximida

*** Taking medicines without doctor's advice can cause long-term problems.
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