Droxicam
Droxicam Uses, Dosage, Side Effects, Food Interaction and all others data.
Droxicam is an oxicam non-steroidal anti-inflammatory drug and a prodrug of Piroxicam. It is used to reduce pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.
Droxicam is a prodrug of Piroxicam . Droxicam administration produces anti-inflammatory, antirheumatic, analgesic, and antipyretic effects similar to Piroxicam.
| Trade Name | Droxicam |
| Generic | Droxicam |
| Droxicam Other Names | Droxicam |
| Type | |
| Formula | C16H11N3O5S |
| Weight | Average: 357.34 Monoisotopic: 357.04194164 |
| Protein binding | Data not available for prodrug. See Piroxicam for information on the active compound. |
| Groups | Withdrawn |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Droxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis .
How Droxicam works
Droxicam is converted to Piroxicam via hydrolysis of the ester group in the intestine . Droxicam administration inhibits the synthesis of prostaglandins by cyclooxygenase enzymes .
Toxicity
Exposure to Droxicam is associated with significantly increased risk of hepatic toxicity resulting in its withdrawal from the market .
Volume of Distribution
Data not available for prodrug. See Piroxicam for information on the active compound.
Elimination Route
Tmax of 7 h. Bioavailability equivalent to Piroxicam which is thought to be completely absorbed in humans based on data from rabbits .
Half Life
Data not available for prodrug. See Piroxicam for information on the active compound.
Clearance
Data not available for prodrug. See Piroxicam for information on the active compound.
Elimination Route
Data not available for prodrug. See Piroxicam for information on the active compound.
Innovators Monograph
You find simplified version here Droxicam
