Cetobemidone
Cetobemidone Uses, Dosage, Side Effects, Food Interaction and all others data.
Cetobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.
| Trade Name | Cetobemidone |
| Generic | Ketobemidone |
| Ketobemidone Other Names | Cetobemidona, Cetobemidone, Cetobemidonum, Ketobemidone |
| Type | |
| Formula | C15H21NO2 |
| Weight | Average: 247.3327 Monoisotopic: 247.157228921 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
How Cetobemidone works
Cetobemidone (Cliradon, Ketogan, Ketodur, Cymidon, Ketorax, &c.) is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.
Toxicity
Base: Rat Intravenous LD50: 10 mg/kg; Mouse Intravenous LD50: 14 mg/kg. Hydrochloride salt: Rat Oral LD50: 215 mg/kg; Rat Intravenous LD50: 40 mg/kg
Elimination Route
34% (oral), 44% (rectal)
Half Life
Plasma half-life: 2.42 +/- 0.41 h (m +/- SD). Elimination half-life: 3.27 +/- 0.32 h
Innovators Monograph
You find simplified version here Cetobemidone
