Cefotiamum

Cefotiamum Uses, Dosage, Side Effects, Food Interaction and all others data.

One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

Cefotiamum is a third generation beta-lactam cephalosporin antibiotic that works by inhibiting bacterial cell wall biosynthesis. It is a broad spectrum antibiotic that is effective against Gram positive and Gram negative bacteria.

Table Of contents

• Cefotiamum
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Cefotiamum
Generic	Cefotiam
Cefotiam Other Names	Cefotiam, Cefotiamum
Type
Formula	C18H23N9O4S3
Weight	Average: 525.628 Monoisotopic: 525.103512339
Protein binding	40%
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Cefotiamum is a cephalosporin antibiotic used to treat a variety of bacterial infections.

For treatment of severe infections caused by susceptible bacteria.

Cefotiamum is also used to associated treatment for these conditions: Susceptible infections

How Cefotiamum works

The bactericidal activity of cefotiam results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).

Toxicity

Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Elimination Route

Rapidly absorbed following intramuscular injection. Bioavailability is 60% following intramuscular injection.

Half Life

Approximately 1 hour.

Innovators Monograph

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