cefizox

cefizox Uses, Dosage, Side Effects, Food Interaction and all others data.

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.

cefizox is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.

Trade Name cefizox
Availability Discontinued
Generic Ceftizoxime
Ceftizoxime Other Names Ceftizoxima, Ceftizoxime, Ceftizoximum
Related Drugs amoxicillin, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin, clindamycin, ceftriaxone, levofloxacin, Augmentin
Weight 1g, 1000mg, 250mg, 500mg, , 1gram
Type Powder, For Solution, Injection
Formula C13H13N5O5S2
Weight Average: 383.403
Monoisotopic: 383.035809931
Protein binding

30% protein-bound across the standard concentration range.

Groups Approved, Withdrawn
Therapeutic Class
Manufacturer Hikma Pharmaceuticals Plc, Barrett Hodgson Pakistan (pvt) Ltd, , Glaxosmithkline, Dankos Farma, Hikma Farmaceutica (portugal), Sa
Available Country Saudi Arabia, Pakistan, India, United States, Indonesia, Portugal,
Last Updated: September 19, 2023 at 7:00 am
cefizox
cefizox

Uses

cefizox is a third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.

Cetizoxime was previously indicated for the treatment of infections due to susceptible strains of bacteria.

cefizox is also used to associated treatment for these conditions: Bacterial Infections

How cefizox works

cefizox is an aminothiazolyl cephalosporin with an extended spectrum of activity against many gram-negative, nosocomially acquired pathogens. It has excellent beta-lactamase stability, with good in vitro activity against Haemophilus influenzae, Neisseria gonorrhoeae and Klebsiella pneumoniae. cefizox, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that ceftizoxime interferes with an autolysin inhibitor.

Food Interaction

No interactions found.

cefizox Hypertension interaction

[Moderate] Parenteral ceftizoxime sodium contains approximately 60 mg (2.6 mEq) of sodium per each gram of ceftizoxime activity.

The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention.

Volume of Distribution

The mean apparent volume of distribution ranges between 15 - 28L.

Elimination Route

Excreted virtually unchanged by the kidneys in 24 hours.

Innovators Monograph

You find simplified version here cefizox

*** Taking medicines without doctor's advice can cause long-term problems.
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