Candoxatril Uses, Dosage, Side Effects and more
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Attribute | Details |
---|---|
Trade Name | Candoxatril |
Generic | Candoxatril |
Candoxatril Other Names | Candoxatril |
Type | |
Formula | C29H41NO7 |
Weight | Average: 515.6383 Monoisotopic: 515.288302671 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | January 7, 2025 at 1:49 am |
How Candoxatril works
Neutral endopeptidase inhibitors such as Candoxatril have a dual mechanism of action. They inhibit two metalloprotease enzymes, neutral endopeptidase and ACE, resulting in an increased availability of natriuretic peptides that exhibit vasodilatory effects and, possibly, tissue protective effects.
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