Biricodar

Biricodar Uses, Dosage, Side Effects, Food Interaction and all others data.

The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).

Biricodar dicitrate blocks two major multi-drug resistance mechanisms: P-glycoprotein (MDR-1) and multi-drug resistance-associated protein (MRP).

Table Of contents

• Biricodar
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Biricodar
Generic	Biricodar
Biricodar Other Names	Biricodar
Type
Formula	C34H41N3O7
Weight	Average: 603.716 Monoisotopic: 603.294450672
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Administered intravenously, biricodar dicitrate is to be used in combination with cancer chemotherapy agents.

How Biricodar works

Vertex’s research shows that biricodar dicitrate can enhance the accumulation of chemotherapy agents in tumor cells by blocking the drug pumps P-gp and MRP, and that it is capable of restoring the sensitivity of tumors to treatment with chemotherapeutic agents.

Innovators Monograph

You find simplified version here Biricodar