Bimoclomol

Bimoclomol Uses, Dosage, Side Effects, Food Interaction and all others data.

Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.

Trade Name Bimoclomol
Generic Bimoclomol
Bimoclomol Other Names Bimoclomol
Type
Formula C14H20ClN3O2
Weight Average: 297.781
Monoisotopic: 297.124404606
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Bimoclomol
Bimoclomol

Uses

Investigated for use/treatment in neuropathy (diabetic) and wounds.

How Bimoclomol works

Bimoclomol binds to HSF-1 and induces a prolonged binding of HSF-1 to the respective DNA elements. Since HSF-1 does not bind to DNA in the absence of stress, the bimoclomol-induced extension of HSF-1/DNA interaction may contribute to the chaperone co-induction of bimoclomol observed previously. These findings indicate that bimoclomol may be of value in targeting HSF-1 so as to induce up-regulation of protective Hsp-s in a non-stressful manner and for therapeutic benefit.

Innovators Monograph

You find simplified version here Bimoclomol

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