Bezitramidum

Bezitramidum Uses, Dosage, Side Effects, Food Interaction and all others data.

Bezitramidum is a narcotic analgesic which was discovered in 1961, clinically tested around the 1970's , and marketed under the name Burgodin. After cases of fatal overdose in the Netherlands in 2004 the drug was withdrawn from the market.

Bezitramidum has never been FDA approved and is currently a schedule II drug.

Bezitramidum acts in the body to relieve pain with a potency 20 times that of methadone . Its duration of action is relatively long, lasting up to 12 hours post oral administration, after the achievement of steady state. Its onset of action is slow, with a peak in analgesic effect noted between 2.5-3.5 hours after dosing.

Table Of contents

• Bezitramidum
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Bezitramidum
Generic	Bezitramide
Bezitramide Other Names	Bezitramida, Bezitramide, Bezitramidum
Type
Formula	C31H32N4O2
Weight	Average: 492.6114 Monoisotopic: 492.252526288
Groups	Experimental, Illicit, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

A narcotic analgesic once used for the treatment of severe chronic pain.

Elimination Route

Bezitramidum has poor water solubility, thus administration is restricted to the oral route.

Half Life

11-24h.

Elimination Route

Less than 0.3% of the dose was excreted unchanged in the urine. High concentrations in feces suggested incomplete absorption of biliary excretion.

Experiments in rats demonstrated extensive (up to 70%) biliary excretion, and less than 3% urinary excretion.

Innovators Monograph

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