Bambuscot Uses, Dosage, Side Effects, Food Interaction and all others data.

Bambuscot is an adrenergic β2 receptor agonist which predominantly stimulates β2 receptor, thus producing relaxation of bronchial smooth muscle, inhibition of release of endogenous spasmogens, inhibition of edema caused by endogenous mediators & increased mucocilliary clearance.

Bambuscot is a long acting beta2-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline. Bambuscot causes smooth muscle relaxation, resulting in dilation of bronchial passages.

Trade Name Bambuscot
Generic Bambuterol
Bambuterol Other Names Bambuterol, bambutérol, Bambuterolum
Weight 10mg, 20mg
Type Tablet
Formula C18H29N3O5
Weight Average: 367.44
Monoisotopic: 367.210721053
Groups Investigational
Therapeutic Class Short-acting selective β2-adrenoceptor stimulants
Manufacturer Scotmann Pharmaceuticals
Available Country Pakistan
Last Updated: September 19, 2023 at 7:00 am


Bambuscot is used for Bronchial asthma, chronic bronchitis, emphysema & other lung diseases where bronchospasm is a complicating factor.

Bambuscot is also used to associated treatment for these conditions: Bronchial Asthma, Bronchospasm, Chronic Bronchitis, Emphysema

How Bambuscot works

The pharmacologic effects of bambuterol are at least in part attributable to stimulation through beta-adrenergic receptors (beta 2 receptors) of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.


Bambuscot dosage

Adult or Elderly: The recommended initial dose 10 mg. The dose may be increased to 20 mg after 1-2 weeks depending on the clinical effect.

Children 2-5 years:The recommended normal dose 10 mg (10 ml syrup).

Children 6-12 years:The recommended normal dose 10 mg (10 ml syrup). The dose may be increased to 20 mg.

Side Effects

Common side effects are fatigue, nausea, palpitation, headache, dizziness & tremor.


Reduce the dose in renal impairment, avoid in cirrhosis and severe hepatic impairment. Caution should be observed in patients with severe cardiovascular disorder, such as ischaemic heart disease, tachyarrhythmias or severe heart failure.


Succinylcholin, MAOIs (monoamine oxidase inhibitors), β2-blockers, corticosteroids, diuretics, muscle relaxants, sympathomimetic xanthine derivatives. Bambuscot may partly or totally inhibit the effect of β-blockers.

Elimination Route

Bioavailability is 20% following oral administration.

Half Life

13 hours for bambuterol and 21 hours for the primary active metabolite terbutaline.

Pregnancy & Breastfeeding use

Pregnant women: There is no definite evidence of ill consequence during pregnancy. Nevertheless, the drug should not be used during the first trimester of pregnancy, unless the expected benefit is thought to outweigh any possible risk to the fetus.

Lactating mother: It is excreted in breast milk. So, patients taking this drug should not breast-feed.


Bambuscot is contraindicated in hepatic impairment, liver cirrhosis or severely impaired liver function.

Special Warning

Impaired renal function (GFR 50 ml/min): The recommended starting dose is 5 mg, which may be increased to 10 mg after one to two weeks, depending on the clinical effect.

Impaired hepatic function: Not recommended because of unpredictable conversion to terbutaline.

Storage Condition

Keep away from light, store in a cool and dry place. Keep out of reach of children.

Innovators Monograph

You find simplified version here Bambuscot

Bambuscot contains Bambuterol see full prescribing information from innovator Bambuscot Monograph, Bambuscot MSDS, Bambuscot FDA label

*** Taking medicines without doctor's advice can cause long-term problems.