Aristobet-N Eye/ear/nasal Drops, Eye Ointment, Ointment

Betamethasone is a synthetic, topical corticosteroid. It has anti-allergic, anti-pruritic and anti-inflammatory activity

Uses

Eye: Inflammatory conditions (eg. uveitis, marginal keratitis, allergic conjunctivitis, blepharitis and episcleritis) where development of bacterial infection is likely.

Ear: Otitis externa and other inflammatory conditions where bacterial infection is present or suspected.

Nose: Inflammatory conditions where infection is present or suspected.

Trade Name Aristobet-N
Generic Betamethasone + Neomycin Sulphate (E/E)
Weight 0.1%+0.5%, 0.1% + 0.5%
Type Eye/ear/nasal Drops, Eye Ointment, Ointment
Therapeutic Class Ophthalmic steroid - antibiotic combined preparations
Manufacturer Aristopharma Ltd
Available Country Bangladesh
Last Updated: June 23, 2021 at 11:17 am

Dosage

Aristobet-N dosage

Adults and children

Eye: 1 or 2 drops to each affected eye every 1 or 2 hours until control is achieved, then the frequency may be reduced.

Ear: 2 or 3 drops to each affected ear every 2 or 3 hours until control is achieved, then the frequency may be reduced.

Nose: 2 or 3 drops instilled into each nostril 2 or 3 times daily.

Side Effects

Hypersensitivity reactions may occur leading to irritation, burning, stinging, itching and dermatitis. Topical corticosteroid use may result in corneal ulceration, increased intraocular pressure leading to optic nerve damage, reduced visual acuity.Intensive or prolonged use of topical corticosteroids may lead to formation of posterior subcapsular cataracts. In those diseases causing thinning of the cornea or sclera, corticosteroid therapy may result in thinning of the globe leading to perforation. Mydriasis, ptosis and epithelial punctate keratitis have also been reported following ophthalmic use of corticosteroids

Precaution

Topical corticosteroids should never be given for an undiagnosed red eye. Ophthalmic treatment with corticosteroid preparations should not be repeated or prolonged without regular review to exclude raised intraocular pressure, cataract formation or unsuspected infections

Pregnancy & Breastfeeding use

There are no adequate and well controlled studies for pregnant woman. It should not be used extensively in pregnant woman. There is no information available whether it is secreted in the milk or not.

Contraindication

Viral, fungal, tuberculous or purulent conditions. Use in the eye is contra-indicated if glaucoma is present or where herpetic keratitis (e.g. dendritic ulcer) is considered a possibility. Inadvertent use of topical steroids in the latter condition can lead to extension of the ulcer and marked visual deterioration. Preparations containing neomycin should not be used for treating otitis externa when the ear drum is perforated, because of the risk of ototoxicity.

Acute Overdose

Long-term intensive topical use may lead to systemic effects

Interaction with other Medicine

Specific drug interaction studies have not been conducted.

Storage Condition

Should be protected from light, store below 25 °C. Keep out of reach of children. Do not use more than 4 weeks after opening

Aristobet-N contains Betamethasone + Neomycin Sulphate (E/E) see full prescribing information from innovator Monograph