Apodin Solution, Lotion, Ointment, Mouthwash

Apodin is an iodophore with a powerful broad-spectrum germicidal activity against a wide range of bacteria, viruses, fungi, protozoa and spores. Microbicidal; oxidizes cell constituents; iodinates proteins and inactivates them.

Uses

Abrasion, Bed sore, Burns, Cuts, Decubitus or stasis ulcers, Leg ulcers and pressure sores, Pre-operative and post-operative skin cleansing, Pre-operative scrubbing & washing, Pre-operative skin disinfection, Pressure sores, Skin infections, Vaginitis, Wound and burn dressing, Wound and ulcer cleansing, Wound cleansing, Wound infection, Wound sepsis, Wounds

Apodin is also used to associated treatment for these conditions: Skin Infections, Skin disinfection, Irrigation of the ocular surface therapy, Prepping of the periocular region, Prophylaxis of bacterial skin infections

Trade Name Apodin
Generic Povidone-iodine
Other Names Iodopovidone, Povidone iodine, Povidone-iodine, Povidone, iodinated, PVP-I
Weight 10% w/v, 5% w/w, 1% w/v
Type Solution, Lotion, Ointment, Mouthwash
Protein binding

To be used topical. No plasma protein binding reported.

Therapeutic Class Iodine compounds (Anti-septic Preparations)
Manufacturer Globe Pharmaceuticals Limited
Available Country Bangladesh
Last Updated: June 23, 2021 at 11:24 am

Dosage

Apodin dosage

Pre-operative scrubbing & washing: Wet hands with water, then pour 5 ml of solution onto the palm and spread over both the hands, rub the scrub over the entire area for about 2 mintues, add water to develope copious suds, rinse throughly under running water.

Pre- and post-operative skin cleansing: After the skin is shaved and wet with water, apply surgical scrub & rub throughly for minimum 2 mintues, rinse of with the sterile gauze saturated with water.

Side Effects

Local skin irritation and sensitivity. Application to large areas of denuded skin may produce systemic effects due to iodine absorption.The application of povidone iodine to large wounds or severe burns may producesystemic adverse effectssuch as metabolic acidosis, hypernatraemia and impairment of renal function.

Precaution

Avoid contact with eyes; should not be used under occlusive dressing. Pregnancy, lactation

Food Interaction

No interactions found.

Volume of Distribution

Povidone-Iodine is intended for topical application and has no volume of distribution.

Half Life

Povidone-Iodine is intended for topical application and is not eliminated.

Clearance

Povidone-Iodine is intended for topical application and is not eliminated.

Pregnancy & Breastfeeding use

Pregnancy Category D. There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Contraindication

Hypersensitivity; prolonged use in patients with thyroid disorders or on lithium therapy. Special caution is needed when regular applications to broken skin are made to patients with pre-existing renal insufficiency. Regular use should be avoided in patients on concurrent lithium therapy.