Apatorsen Uses, Dosage, Side Effects and more

Apatorsen is a second generation antisense drug which in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human cancers including prostate, lung, breast, ovarian, bladder, renal, pancreatic, multiple myeloma and liver cancer.

OGX-427 significantly decreases levels of Hsp27, induces apoptosis in several human cancer cell lines, has single agent anti-tumor activity, and acts as a chemosensitizer in combination with several cytotoxic drugs including docetaxel.

Attribute	Details
Trade Name	Apatorsen
Generic	Apatorsen
Apatorsen Other Names	Apatorsen
Type
Formula	C224H304N79O116P19S19
Weight	Average: 7156.97 Monoisotopic: 7152.002582293
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	January 7, 2025 at 1:49 am

Uses

Investigated for use/treatment in cancer/tumors (unspecified).

Innovators Monograph