Anaroxyl Tablet, Injection

Anaroxyl is a haemostatic with a rapid onset of action. It contains a water soluble form of adrenochrome monosemicarbazone, a stable derivative of adrenochrome as the active substance. Adrenochrome is an oxidation product of adrenaline; it reduces normal and pathologic bleeding time by decreasing capillary permeability. It produces capillary haemostatis without exerting any of the adrenergic actions on respiration or cardiovascular system. Thus, despite its adrenaline like action on small blood vessels, does not give rise to the general systemic effects of sympathomimetic drugs.

Uses

Adrenochrome is used for control capillary bleeding, haemoptysis, epistemic, haematuria, retinal hemorrhage, secondary hemorrhage from wounds

Trade Name Anaroxyl
Generic Adrenochrome Monosemicarbazone
Weight 2.5mg, 5mg/ml,
Type Tablet, Injection
Therapeutic Class Anti-fibrinolytic drugs
Manufacturer Nuvista Pharma Ltd, Nuvista Pharma Ltd,, Obs
Available Country Bangladesh, Pakistan,
Last Updated: June 23, 2021 at 11:16 am

Dosage

Anaroxyl dosage

Oral (Adult)-

  • As a haemostatic: 10-30 mg tid.

Injection (Adult)-

  • As a haemostatic: 10 mg daily by SC/IM inj. Alternatively, 25-100 mg daily by IV Inj or drip infusion.
  • Pre-operative: 2-6 ml at suitable intervals.
  • Post-operative: 1-2 ml every 2 hrs.
  • Non-surgical: 2-4 ml tid.

Injection (Child <6 years): 1-2 ml tid.

Side Effects

Allergic reactions may occur like dyspnoea, bronchospasm, skin reaction etc.

Precaution

Because of the content of diprophylline (90 mg/ml), the dosage to premature babies, infants and young children should not exceed 0.3 ml.

Interaction

No specific drug interaction has been demonstrated.

Pregnancy & Breastfeeding use

Pregnancy Category-Not Classified. FDA has not yet classified the drug into a specified pregnancy category

Contraindication

Should not be administered to patients with hypersensitivity