Anabolin Injection, Im Injection

Nandrolone is an anabolic steroid. It promotes tissue-building processes and protein anabolism. It also stimulates erythropoeitin production, causing an increase in haemoglobin and RBC volume.

Uses

Nandrolone decanoate is used for the management of the anemia of renal insufficiency and has been shown to increase hemoglobin and red cell mass. Surgically induced anephric patients have been reported to be less responsive.

Anabolin is also used to associated treatment for these conditions: Chronic renal failure anemia, Osteoporosis (Senile), Postmenopausal Osteoporosis

Trade Name Anabolin
Generic Nandrolone Decanoate
Other Names Nandrolone decanoate
Weight 25mg/ml
Type Injection, Im Injection
Formula C28H44O3
Weight Average: 428.6472
Monoisotopic: 428.329045274
Protein binding

Data regarding the percent protein binding of nandrolone decanoate is not readily available. After nandrolone decanoate is hydrolyzed to nandrolone, it is bound to sex hormone binding globulin.

Therapeutic Class Anabolic steroid, Anabolic steroid (Androgens), Hormone in bone formation by stimulation
Manufacturer Techno Drugs Ltd, Techno Drugs Ltd,
Available Country Bangladesh
Last Updated: June 23, 2021 at 11:23 am

Dosage

Anabolin dosage

Anaemia in chemotherapy patients: 50-150 mg wkly.

Anabolic after debilitating illness, Postmenopausal osteoporosis, Metastatic breast cancer: 25-100 mg once every 3-4 wk.

Anaemia of chronic renal failure: 50-200 mg wkly.

Side Effects

Male: Postpubertal: Acne, gynaecomastia, bladder irritability, priapism, insomnia, chills, decreased libido, hepatic dysfunction, nausea, diarrhoea, prostatic hyperplasia. 

Prepubertal: Acne, virilism, chills, insomnia, hyperpigmentation, diarrhoea, nausea. 

Female: Virilism, hypercalcaemia, nausea, diarrhoea, chills, insomnia, iron deficiency anaemia, hepatic dysfunction.

Precaution

Monitor diabetic patients carefully. Conditions influenced by oedema (e.g. CV disease, migraine, seizure disorder, renal impairment). Hepatic impairment. Elderly. Discontinue if signs of virilisation in women occur. Monitor skeletal maturation in children.

Interaction

May increase effects of oral anticoagulants, insulin, oral antidiabetic agents, adrenal steroid, adrenocorticotropic hormone (ACTH).

Food Interaction

No interactions found.

Half Life

Nandrolone decanoate has an absorption half life of 6 days and an elimination half life of 4.3 hours. Alternate studies have shown that nandrolone decanoate has a terminal half life of 7.1, 11.7, and 11.8 hours for doses of 50, 100, and 150 mg respectively.

Clearance

50 mg, 100 mg, and 150 mg doses of nadrolone decanoate had mean apparent clearances of 80.0 L/h, 74.3 L/h, and 76.2 L/h respectively.

Pregnancy & Breastfeeding use

Pregnancy Category X. Studies in animals or human beings have demonstrated foetal abnormalities or there is evidence of foetal risk based on human experience or both, and the risk of the use of the drug in pregnant women clearly outweighs any possible benefit. The drug is contraindicated in women who are or may become pregnant.

Contraindication

Prostatic or breast carcinoma (male); nephrosis, porphyria; infants, pregnancy and lactation.

Anabolin contains Nandrolone Decanoate see full prescribing information from innovator Monograph