Algin Tablet, Syrup, Im/iv Injection

Tiemonium are quaternary ammonium antimuscarinic agent with peripheral effect similar to those of atropine. Tiemonium strengthens calcium bonding with phospholipids and proteins thus stabilizing the cell membrane of the GI tract.

Uses

Algin is an antispasmodic drug. It reduces muscle spasms of the intestine, biliary system, uterus & urinary bladder. It is used for the pain in gastrointestinal, biliary, urinary and gynecological disease such as gastroenteritis, diarrhea, dysentery, biliary colic, enterocolitis, cholecystytis, colonopathies, mild cystitis, & spasmodic dysmenorrhoea.

Trade Name Algin
Generic Tiemonium Methylsulphate
Weight 50mg, 10mg/5ml, 5mg/2ml
Type Tablet, Syrup, Im/iv Injection
Therapeutic Class Anticholinergics
Manufacturer Renata Limited
Available Country Bangladesh
Last Updated: June 23, 2021 at 11:25 am

Dosage

Algin dosage

Tablet: Recommended oral dose of Algin tablet is 2-6 tablets (100-300 mg) daily in divided dose.

Injection: Recommended injectable dose is 1 Algin Injection 3 times daily, through Intravenous route slowly or Intramuscular route.

Syrup

  • Children: 3 mg to 6 mg/kg/day or 1.5 ml to 3 ml/kg/day in 3 divided doses.
  • Adult: 30 mg to 90 mg or 15 ml to 45 ml 3 times daily or as directed by physician.

Suppository: Recommended dose is 20 mg Algin suppository two or three times daily, through rectal route.

Side Effects

Side effect with the use of Algin is very rare.

Precaution

Precautions should be exercised for treatment of patients with disorders of prostate, chronic bronchitis, coronary insufficiency, ambient hyperthermia, cardiac disorders, thyroid disorders, serious renal & hepatic insufficiency.

Interaction

Algin should not be used with other drugs without prior consult of a registered physician to avoid possible drug interaction.

Pregnancy & Breastfeeding use

Algin may be used in pregnancy only if it is clearly needed by the assessment of risk benefit ratio. Algin may be used in lactating mother only if it is clearly needed by the assessment of risk benefit ratio.

Contraindication

Algin should not be used in Glucoma or where acute pain of eyeball with vision disturbance was found. This drug should also not be used in patients with the disorder of prostate or urinary bladder.

Special Warning

Paediatric use: safety and effectiveness of Tiemonium methylsulphate in paediatric patients have not been established.

Geriatric use: Efficacy and safety were maintained with increasing age.

Acute Overdose

Occasional retention of urine may occur in case of overdoses.

Storage Condition

Keep it in a cool and dry place, protected from light and moisture. Keep all medicines away from the reach of the children.

FAQ

What is the properties of Algin?

Algin (Tiemonium Methylsulphate) a competitive antagonist of Acetylcholine, Histamine and strengthens of calcium bond with membrane phospholipids and proteins. Thus inhibits intracellular contractile protein of visceral cell which causes inhibition of visceral spasm and pain.

Does Algin safe in pregnancy?

Algin is not recommended during pregnancy and lactation, unless otherwise indicated by physician. Algin may have some undesirable effects in certain individuals like risk of hypotension and tachycardia if ingested in high doses rapidly.

What are the side effects of Algin?

Algin may have some undesirable effects in certain individuals like risk of hypotension and tachycardia if ingested in high doses rapidly.

Does Algin safe in breast feeding?

Algin is not recommended during pregnancy and lactation, unless otherwise indicated by physician.

Why does Algin used for?

Algin is used for visceral muscle spasm e.g.

  • Spasms of the intestine, biliary system, bladder and uterus

It is also indicated for

  • Gastroenteritis, diarrhoea, dysentery
  • Enterocolitis, cholecystitis, colonopathies, biliary colic
  • Mild cystitis, symptomatic nephritic colic
  • Spasmodic dysmenorrhoea

What is Algin?

Algin (often used in a form of iodide or methylsulphate salt) is a muscarinic acetylcholine receptor antagonist, which is available in Asia (mainly Bangladesh) for the alleviation of muscle spasms of the intestine, biliary system, uterus and urinary bladder in gastrointestinal, biliary, urinary and gynecological.

How does Algin work?

Algin prevents the effects of acetylcholine by blocking its binding to muscarinic cholinergic receptors at neuroeffector sites on smooth muscle of GI tract 2, regardless of their function and innervations.