Mudiral Tablet

Mudiral Tablet is manufactured by Opsonin Pharma Ltd. Mudiral Tablet contains 100 mg Sertraline. It is SSRIs & related anti-depressant drugs class drug.

Mudiral has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites. It ultimately results in an improvement of depression. Reduction of Serotonin turnover in brain by Mudiral is also another contributing fact implicated in its action. Its prolonged elimination half-life offers a benefit of once daily administration.

Uses

Mudiral is used for Depressive illness, Obsessive-compulsive disorder, Post-traumatic stress disorder, Panic disorder

Brand Name: Mudiral
Generic: Sertraline
Weight: 100 mg
Type: Tablet
Therapeutic Class: SSRIs & related anti-depressant drugs
Manufacturer: Opsonin Pharma Ltd
Price: 12.60
Last Updated: November 19, 2020 at 6:15 pm

Dosage

Mudiral contains Sertraline 100 mg. Mudiral Dosage:

Depressive illness: 

  • Adult: Initially 50 mg daily, increased if necessary by increments of 50 mg over several weeks to maximum 200 mg daily. Usual maintenance dose is 50 mg daily.
  • Child and adolescent less than 18 years: Not recommended.

Obsessive-compulsive disorder: 

  • Adult and adolescent over 13 years: Initially 50 mg daily, increased if necessary in steps of 50 mg over several weeks. Usual dose range is 50-200 mg daily.
  • Child (6-12 years): Initially 25 mg daily, increased to 50 mg daily after 1 week, further increased if necessary in steps of 50 mg at intervals of at least 1 week (maximum 200 mg daily).

Post-traumatic stress disorder:

  • Adult: Initially 25 mg daily, increased after 1 week to 50 mg daily; if response is partial and if drug is tolerated, dose can be increased in steps of 50 mg over several weeks to maximum 200 mg daily.
  • Child and adolescent less than 18 years: Not recommended.

 

Side Effects

Mudiral may cause side effects like upset stomach, diarrhoea, constipation, vomiting, dry mouth, loss of appetite, weight changes, drowsiness, dizziness, headache, pain, burning or tingling in the hands or feet, excitement, sore throat etc.

Precaution

Precaution should be taken in case of liver problems, kidney diseases, seizures, heart problems and any allergies. This drug may cause dizziness or drowsiness. Caution should be taken in activities requiring alertness such as driving or using machinery. Caution is advised while using this product in the elderly because they may be more sensitive to the effects of the drug. Do not take this drug if you have taken monoamine oxidase inhibitor in the last five weeks.

Mudiral

Interaction

Potential effects of co-administration of drugs that are highly bound to plasma proteins- As Mudiral is tightly bound to plasma protein, the administration of Mudiral to a patient taking another drug which is tightly bound to protein, (e.g. warfarin, digitoxin) may cause a shift in plasma concentrations potentially resulting in an adverse effect. Conversely adverse effects may result from displacement of protein bound Mudiral by other tightly bound drugs. Mudiral may interact with other drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol etc.

Pregnancy Lactation use

Pregnancy: Although animal studies did not provide any evidence of teratogenicity, the safety of Mudiral during human pregnancy has not been established. 

Lactation: Mudiral is known to be excreted in breast milk. Its effects on the nursing infant have not yet been established. If treatment with Mudiral is considered necessary, discontinuation of breast-feeding should be considered.

Contraindication

Mudiral is contraindicated in patients with a known hypersensitivity to Mudiral or any of the excipients of drug.

Special Warning

 

Acute Overdose

 

Interaction with other Medicine

 

Storage Condition

Store at 25° C.

FAQ

What are the side effects for Mudiral?

Mudiral may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea
  • diarrhea
  • constipation
  • vomiting
  • difficulty falling asleep or staying asleep
  • dry mouth
  • heartburn
  • loss of appetite
  • weight changes
  • dizziness
  • excessive tiredness
  • headache
  • nervousness
  • uncontrollable shaking of a part of the body
  • changes in sex drive or ability
  • excessive sweating

What should I do if I forget to take Mudiral?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Is Mudiral a strong antidepressant?

Mudiral (sertraline) is a good and safe antidepressant that is also used to treat other psychiatric disorders such as panic disorder, post-traumatic stress disorder and obsessive compulsive disorder.

Is Mudiral good for anxiety?

A study in The Lancet Psychiatry found that taking Mudiral leads to an early reduction in anxiety symptoms, commonly found in depression, several weeks before any improvement in depressive symptoms.

Does Mudiral make you happy?

Mudiral will not change your personality or make you feel euphorically happy. It'll simply help you feel like yourself again. Do not expect to feel better overnight, though. Some people feel worse during the first few weeks of treatment before they begin to feel better.

Can I take Mudiral at night?

Mudiral is designed for use once per day. It's safe to take it at any time of day, with or without food. Many people who experience nausea and other side effects from Mudiral opt to take it at night in order to limit these side effects.

What can't I take with Mudiral?

Some products that may interact with this drug are: pimozide, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, "blood thinners" such as warfarin/dabigatran).

Why does Mudiral make gain weight?

One potential theory is that antidepressants like Mudiral can make you feel hungrier than normal. People who use Mudiral might also feel less satisfied after eating food, resulting in them eating bigger portions that contain a larger amount of calories.

Why is Mudiral making me so tired?

Fatigue and tiredness are two of the most common side effects of Mudiral, as well as several other SSRIs. If you're using Mudiral to treat depression, fatigue and tiredness from the medication can also be compounded by the effects of depression on your mood.

Will Mudiral calm me down?

Mudiral should help you feel calm and relaxed. It could take some time for Mudiral to have its full effect. This effect should reduce your behavior problem.

Can Mudiral work immediately?

Mudiral doesn't work immediately, so don't stop taking Mudiral if your symptoms don't improve right away. It takes two to six weeks to start reducing anxiety symptoms. Some people may feel a reduction in their anxiety symptoms within the first week of taking Mudiral, but this shouldn't be expected for everyone.

What happens if I drink alcohol with sertraline?

You should not mix alcohol with Mudiral. Combining the two can make you feel very drowsy, which can be dangerous. The combination can also raise your risk of other dangerous or unpleasant side effects from Mudiral. Even if you don't take Mudiral, you shouldn't drink alcohol if you have depression.

Is Mudiral a addictive?

Since Mudiral is a long-term antidepressant, it is not considered an addictive or narcotic substance. The potential for abuse is low according to psychiatrists, even though it is a mind-altering substance. Taken properly and as prescribed, Mudiral carries very little risk for abuse or addiction.

Does Mudiral give me energy?

It can improve sleep quality, appetite, energy levels, restore interest in daily life, and reduce unwanted thoughts and panic attacks. Mudiral is available in tablet form in dosage strengths of 25 mg, 50 mg, or 100 mg.

How long does Mudiral last in my body?

Mudiral last 5.4 days in our body and half life is about 26 hours. 

Does Mudiral make me sleepy?

You can feel drowsy in the first few days of taking Mudiral. This should get better after the first week or two. If it makes you feel drowsy, try taking it just before you go to bed. You could also, strangely, get insomnia (difficulty getting to sleep), and disturbing dreams or nightmares.

Can I take paracetamol with Mudiral?

It is OK to take Paracetamol with Mudiral, but if you are taking other kinds of medication every day you need to let your doctor know, as they may interact with Mudiral and change its effect on your body.

Can I stop Mudiral after 2 days?

After one day, the level is reduced to 50 percent of the original level, after two days to 25 percent, after three days to 12.5 percent, and so on. Because Mudiral leaves your body so quickly, stopping it too abruptly can cause discontinuation syndrome to develop.

Can I take 2 50mg Mudiral?

Talk to your doctor about any other medications you may be taking. You should never take two doses of Mudiral at the same time, as it can lead to an accidental overdose.

Can I drink coffee with Mudiral?

No interactions were found between caffeine and Mudiral. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Why is Mudiral making me sick?

When serotonin levels increase under the influence of SSRIs, they stimulate serotonin receptors in the GI tract as well as the brain. The combined stimulatory effect—on both the GI tract and CNS—can trigger such side effects as: Diarrhea. Loss of appetite (anorexia)

Can Mudiral become ineffective?

If you feel like your antidepressant has stopped working, you're not alone. It's common for a medication that once worked wonders to become ineffective, especially if you've been taking it for a long time. Symptoms return for up to 33% of people using antidepressants — it's called breakthrough depression.

Is Mudiral a powerful drug?

Mudiral are powerful prescription medications used to treat depression and other issues. They're both Mudiral-name drugs. The generic version of Mudiral is fluoxetine, while the generic version of Mudiral is sertraline hydrochloride. Both drugs are selective serotonin reuptake inhibitors (SSRIs).

Can Mudiral cause memory loss?

Most common side effects are agitation, hallucinations, fever, overactive reflexes, tremors; nausea, vomiting, loss of appetite, feeling unsteady, loss of coordination; trouble concentrating, memory problems, weakness, fainting, seizure, shallow breathing, or breathing that stops.

Does Mudiral really work?

Studies show that Mudiral is an effective treatment for social anxiety disorder. In a 2006 study, researchers found that Mudiral performed significantly better than a non-therapeutic placebo in reducing social anxiety symptoms.

What happens if I suddenly stop taking sertraline?

Stopping Mudiral abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin). Depression is also a part of bipolar illness.

How can I reduce the side effects of Mudiral?

Consider these strategies:

  • Take a brief nap during the day.
  • Get some physical activity, such as walking.
  • Avoid driving or operating dangerous machinery until the fatigue passes.
  • Take your antidepressant at bedtime if your doctor approves.
  • Talk to your doctor to see if adjusting your dose will help.

Can I take Mudiral during pregnancy?

Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Mudiral). Potential complications include maternal weight changes and premature birth.

Can Mudiral give me night sweats?

Antidepressants are a common medication that can lead to night sweats with as many as 22% of people taking antidepressants reporting night sweats as a side effect (especially Mudiral and venlafaxine).

What does Mudiral treat?

Mudiral is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). It's often used to treat depression, and also sometimes panic attacks, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD).

Why should not take Mudiral on a night?

Many people who experience nausea and other side effects from Mudiral opt to take it at night in order to limit these side effects. Since Mudiral can interfere with sleep in a small percentage of users, many people also opt to take Mudiral in the morning.

What are long term side effects of Mudiral?

Possible side effects include:

  • Dry mouth.
  • Constipation.
  • Weight gain or loss.
  • Bladder problems.
  • Sexual problems.
  • Blurred vision.
  • Drowsiness.