Azitac contains Azithromycin. Azitac uses:
Azitac is indicated for infections caused by susceptible organisms in-
Upper respiratory tract infections including sinusitis, pharyngitis and tonsillitis
Lower respiratory tract infections including bronchitis, acute bacterial exacerbations of chronic obstructive pulmonary
Skin and soft tissue infections including cellulitis, pyoderma, erysipelas, wound infections
Sexually transmitted diseases, especially in the treatment of non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis
Genital ulcer disease in men due to Haemophilus ducreyi (chancroid)
Mild or moderate typhoid due to multiple-antibacterial resistant organisms
Prophylaxis against a-hemolytic (viridans group) streptococcal bacterial endocarditis
Other infections including odontogenic infections, bartonella infections, toxoplasmosis, babesiosis
|Manufacturer:||Unimed Unihealth MFG. Ltd|
|Last Updated:||November 21, 2020 at 6:15 pm|
Azitac is an azalide antibiotic, a subclass of macrolide antibiotic. It acts by binding to the 50s ribosomal subunit of susceptible microorganisms and thus interfering with microbial protein synthesis. Azitac has been shown to be active against most strains in the following microorganisms, both In vitro and in clinical infections:
Gram-positive microorganisms: Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes.
Gram-negative microorganisms: Haemophilus ducreyi, Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae, Escherichia coli.
Other microorganisms: Chlamydia pneumoniae, Chlamydia trachomatis, Mycoplasma pneumoniae, Bacteroides fragilis, Legionella pneumophila, oxoplasma gondii.
Azitac contains Azithromycin 500 mg. Azitac Dosage:
Azitac tablet can be taken with or without food. Azitac suspension should be taken at least 1 hour before or 2 hours after meal.
For respiratory tract infections, otitis media and skin & soft tissue infections: 500 mg once daily for 3 days or an alternative to this as 500 mg once on day 1, followed by 250 mg once daily for next 4 days. For sexually transmitted diseases like genital ulcer, non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis : a single 1 gm (1000 mg) dose. For the treatment of urethritis and cervicitis due to Neisseria gonorrhoeae : a single 2 gm (2000 mg) dose. In typhoid, 500 mg once daily for 7 days. In Cholera, a single 1 gm (1000 mg) dose. In Shigellosis, 500 mg once on day 1, followed by 250 mg once daily for next 4 days.
Azitac can be taken with or without food.
To reconstitute Azitac 15 ml powder for suspension: Add 10 ml or 2 tea spoonfuls of just boiled and cooled water to the content of the bottle and shake well to mix uniformly.
To reconstitute Azitac 30 ml powder for suspension: Add 20 ml or 4 tea spoonfuls of just boiled and cooled water to the content of the bottle and shake well to mix uniformly.
To reconstitute Azitac 50 ml powder for suspension: Add 35 ml or 7 tea spoonfuls of just boiled and cooled water to the content of the bottle and shake well to mix uniformly.
Azitac is well tolerated with a low incidence of side efects. The side effects include nausea, vomiting, abdominal discomfort (pain/cramps), flatulence, diarrhea, headache, dizziness, and skin rashes and are reversible upon discontinuation of therapy. Reversible elevations in liver transaminases have been observed occasionally. Transient mild reductions in neutrophil counts have occasionally been observed in clinical trials, although causal relationship to Azitac has not been established.
As with any antibiotic, observation for signs of super infection with non-susceptable organisms, including fungi, is recommended. Precaution should be taken in patients with more severe renal impairment.
Antacids: Peak serum levels but not the total extent of absorption are reduced by aluminium and magnesium containing antacids in the stomach. Azitac should therefore be taken at least 1 hour before or 2 hours after taking these antacids.
Ergot Derivatives: Because of the theoretical possibility of ergotism, concomitant administration of ergot derivatives and Azitac should be avoided. Digoxin & Cyclosporin: Macrolides have been known to increase the plasma concentration of Digoxin & Cyclosporin and so caution should be exercised while co-administration is necessary.
Anti-Histamines: A potentially life threatening interaction between erythromycin and terfenadine or astemizole have been reported. Although such an interaction with Azitac is not established yet, it is wise to avoid concomitant use of Azitac and terfenadine or astemizole.
Pregnancy Lactation use
Pregnancy: US FDA pregnancy category B. In the animal studies, no evidence of harm to the fetus due to Azitac was found. Because animal reproduction studies are not always predictive of human response, Azitac should be used during pregnancy only if clearly needed.
Lactation: It is not known whether Azitac is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Azitac is administered to nursing mother.
Azitac is contraindicated in patients hypersensitive to Azitac or any other macrolide antibiotic. Co-administration of ergot derivatives and Azitac is contraindicated. Azitac is contraindicated in patients with hepatic diseases.
Pediatric Use: Azitac oral dosage forms can be administered to pediatric patients from 6 months of age. Safety and effectiveness of azithromycin for injection in children or adolescents under 16 years have not been established.
There are no data available on overdose with Azitac. Typical symptoms of overdosage with macrolide antibiotics include hearing loss, severe nausea, vomiting and diarrhoea. Gastric lavage and general supportive measures are indicated.
Interaction with other Medicine
Peak serum levels but not the total extent of absorption were reduced by the presence of magnesium and aluminum-containing antacids. Azitac should be taken at least 1 hr before or 2 hrs after these antacids. In patients receiving ergot alkaloids, Azitac should be avoided concurrently because of the possibilty of ergotism result in from interaction of Azitac with the cytochrome P-450 system However, no cases of such interaction have been reported. Macrolides have been known to increase the plasma concentration of digoxin and cyclosporine. Therefore, if co-administration is necessary caution should be exercised and serum levels of digoxin and cyclosporine should be checked. There have been no pharmacokinetic drug interactions between Azitac and warfarin, theophylline, carbamazepine, methylprednisolone and cimetidine.
Azitac IV infusion: When diluted according to the instructions, azithromycin for injection is stable for 24 hours at or below room temperature 30° C, or for 7 days if stored under refrigeration 5° C.
Azitac capsule, tablet and dry powder for suspension: should be stored at room temperature (below 30° C). Any unused portion of reconstituted Azitac suspension should be discarded after 5 days.
Azitac eye drops: Store unopened bottle under refrigeration at 2°C to 8°C. Once the bottle is opened, store at 2°C to 25°C for up to 14 days. Discard after the 14 days.
Azitac Tablet price in Bangladesh 0.00
How Does Azitac Work?
Azitac prevents the growth of bacteria by interfering with their protein synthesis. It binds to a specific part of the bacterial nucleus and inhibits the process required for bacterial growth. Thereby, bacteria are killed, or their growth is stalled depending on the organism and the medicine concentration.
Can I drive if I have consumed Azitac?
You may drive, but be sure you are not experiencing dizziness before you start driving.
Can I take Azitac while breastfeeding?
Azitac partially passes into human breast milk. If you are taking Azitac then stop breastfeeding your baby. It is advised to discard the milk during treatment and until two days after discontinuation of treatment. You can restart breastfeeding thereafter.
Can I take Azitac during pregnancy?
The safety of Azitac during pregnancy is yet to establish. Azitac is not recommendable in pregnancy. Ask your doctor before taking this medicine.
Can Azitac treat cold?
Azitac is used to treat a wide variety of bacterial infections. It is a macrolide-type antibiotic. It works by stopping the growth of bacteria. This medication will not work for viral infections (such as common cold, flu).
How safe is Azitac?
The U.S. Food and Drug Administration (FDA) is warning the public that azithromycin (Zithromax or Zmax) can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm. source
Does Azitac make me tired?
Azitac oral tablet doesn't cause drowsiness, but it can cause other side effects.
Does Azitac kill gut bacteria?
Like all broad-spectrum antibiotics, Azitac does not discriminate between pathogenic bacteria and healthy bacteria. Hence, when you take antibiotics to fight an infection, many of the bacteria in your gut are killed too (think of it as collateral damage).
Who should not take Azitac?
The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:
- diarrhea from an infection with Clostridium difficile bacteria
- low amount of magnesium in the blood
- low amount of potassium in the blood
- myasthenia gravis, a skeletal muscle disorder
- hearing loss
- torsades de pointes, a type of abnormal heart rhythm
- slow heartbeat
- prolonged QT interval on EKG
- abnormal EKG with QT changes from birth
- a narrowing of the opening between the stomach and the small intestine
- liver problems
- abnormal liver function tests
- inflammation of the liver with stoppage of bile flow
- a yellowing of the eyes or skin from buildup of bilirubin called jaundice
How quickly does Azitac work?
Azitac typically takes at least five days to fully work, but it can start to relieve your sore throat and other symptoms on the first day you take it. If your doctor prescribes a generic version of Azitac, your treatment may only last three days.
What is the side effect of Azitac?
Stomach upset, diarrhea/loose stools, nausea, vomiting, or abdominal pain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Is Azitac a steroid or antibiotic?
Azitac is an antibiotic medication used for the treatment of a number of bacterial infections.
What is Azitac used to treat?
Azitac is an antibiotic. It's widely used to treat chest infections such as pneumonia, infections of the nose and throat such as sinus infection (sinusitis), skin infections, Lyme disease, and some sexually transmitted infections.