Artica Syrup

Artica Syrup is manufactured by ACI Limited. Artica Syrup contains 10 mg/5 ml Hydroxyzine Hydrochloride. It is Sedating Anti-histamine class drug.

Hydroxyzine, a piperazine derivative, blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and resp. It is a sedating antihistamine w/ antimuscarinic and significant sedative properties. It also possesses skeletal muscle relaxing, bronchodilator, antiemetic and analgesic properties.


For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus.

As a sedative when used as premedication and following general anesthesia, hydroxyzine may potentiate meperidine and barbiturates, so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis. Atropine and other belladonna alkaloids are not affected by the drug. Hydroxyzine is not known to interfere with the action of digitalis in any way and it may be used concurrently with this agent.

The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient.

Brand Name: Artica
Generic: Hydroxyzine Hydrochloride
Weight: 10 mg/5 ml
Type: Syrup
Therapeutic Class: Sedating Anti-histamine
Manufacturer: ACI Limited
Price: 56.21
Last Updated: November 20, 2020 at 6:15 pm


Artica contains Hydroxyzine Hydrochloride 10 mg/5 ml. Artica Dosage:

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested: 

  • Adults: 50-100 mg q.i.d.
  • Children under 6 years: 50 mg daily in divided doses
  • Over 6 years: 50-100 mg daily in divided doses

For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus: 

  • Adults: 25 mg t.i.d. or q.i.d.
  • Children under 6 years: 50 mg daily in divided doses
  • Over 6 years: 50-100 mg daily in divided doses

As a sedative when used as a premedication and following general anesthesia: 

  • Adults: 50-100 mg
  • Children: 0.6 mg/kg of body weight

When treatment is initiated by the intramuscular route of administration, subsequent doses may be administered orally. As with all medications, the dosage should be adjusted according to the patient's response to therapy.

May be taken with or without food.

Side Effects

Side effects reported with the administration of hydroxyzine hydrochloride are usually mild and transitory in nature.

Anticholinergic: Dry mouth.

Central Nervous System: Drowsiness is usually transitory and may disappear in a few days of continued therapy or upon reduction of the dose. Involuntary motor activity including rare instances of tremor and convulsions have been reported, usually with doses considerably higher than those recommended. Clinically significant respiratory depression has not been reported at recommended doses.


Patient with porphyria, suffering from glaucoma, bladder outflow obstruction, decreased GI motility, myasthenia gravis, or dementia; with known predisposing factor to cardiac arrhythmia, including electrolyte imbalance, increased potential for convulsions, and pre-existing heart disease. Do not admin via SC, IV, or intra-arterial inj. Renal and hepatic impairment.



Additive or may potentiate CNS depressant effects of opiates or other analgesics, barbiturates or other sedatives, and anaesth. MAOIs and TCAs potentiate antimuscarinic effects.

Pregnancy Lactation use

Pregnancy Category C. Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Nursing mothers: It is not known whether this drug is excreted in human milk. Since many drugs are so excreted, hydroxyzine should not be given to nursing mothers.


Hydroxyzine, when administered to the pregnant mouse, rat, and rabbit, induced fetal abnormalities in the rat and mouse at doses substantially above the human therapeutic range. Clinical data in human beings are inadequate to establish safety in early pregnancy. Until such data are available, hydroxyzine is contraindicated in early pregnancy. Hydroxyzine is contraindicated for patients who have shown a previous hypersensitivity to it.

Special Warning

Renal Impairment: Moderate to severe: Reduce dose by 50%.

Hepatic Impairment: Oral: Reduce total daily dose by 33%.

Geriatric use: A determination has not been made whether controlled clinical studies of hydroxyzine included sufficient numbers of subjects aged 65 and over to define a difference in response from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.

The extent of renal excretion of hydroxyzine has not been determined. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selections. Sedating drugs may cause confusion and over sedation in the elderly; elderly patients generally should be started on low doses of hydroxyzine and observed closely.

Acute Overdose

Symptoms: Excessive sedation, hypotension (rare).

Management: Symptomatic and supportive treatment. Empty stomach immediately by inducing emesis or by gastric lavage. Admin IV fluids and norepinephrine or metaraminol if hypotension occurs.

Interaction with other Medicine


Storage Condition

Store between 15-30° C. Protect from light.


What does Artica used for?

Artica is used in adults and children to relieve itching caused by allergic skin reactions. It is also used alone or with other medications in adults and children to relieve anxiety and tension.

Does Artica a sleeping pill?

Artica is an antihistamine. It is approved for the treatment of anxiety. However, Artica is also used to treat difficulty sleeping, nausea, itching, and allergies.

Does Artica make me sleepy?

As an antihistamine, Artica blocks the effects of histamine in your body, which makes you sleepy. 

Does Artica make you sleepy the next day?

It makes your groggy, sleepy, and the next day you feel tired. Its the same way with Vistaril.

Does Artica bad for my heart?

Artica can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS.

Does Artica a muscle relaxer?

Artica has demonstrated bronchodilator activity (opening up of the airways); antihistaminic (relieves symptoms of allergy including itch), antiemetic (relieves nausea and vomiting), and analgesic (pain relieving) effects; as well as skeletal muscle relaxation.

Can Artica used to treat depression?

Artica is also used to treat itching caused by allergic reactions, to induce sedation prior to or after anesthesia, and to treat nausea, vomiting, and alcohol withdrawal. Buspirone may also help improve symptoms of depression in patients with generalized anxiety disorder. 

What does Artica do for anxiety?

Artica is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery.

What are the side effects to Artica?

Side Effects

  • Chest pain or discomfort.
  • hives, itching, or skin rash.
  • irregular or slow heart rate.
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue.

Can Artica cause depression?

One study of 92 people with chronic itchiness saw that patients who took the antihistamines cetirizine and hydroxyzine reported an increase in depression and anxiety.

Can Artica cause mood swings?

Artica side effects, including: mental/mood changes (such as restlessness, confusion, hallucinations), shaking (tremor), difficulty urinating, fast/irregular heartbeat. Get medical help right away if you have any very serious side effects, including: seizures.