Ariprex Oral Solution

Ariprex Oral Solution is manufactured by Square Pharmaceuticals Ltd. Ariprex Oral Solution contains 1 mg/ml Aripiprazole. It is Atypical neuroleptic drugs class drug.

Ariprex (Ariprex) is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.

Uses

Schizophrenia

Schizoaffective disorder

Acute manic and mixed episodes associated with Bipolar I Disorder

Maintaining efficacy in patients with Bipolar I Disorder who are stabilized

Brand Name: Ariprex
Generic: Aripiprazole
Weight: 1 mg/ml
Type: Oral Solution
Therapeutic Class: Atypical neuroleptic drugs
Manufacturer: Square Pharmaceuticals Ltd
Price: 105.00
Last Updated: November 21, 2020 at 6:15 pm

Dosage

Ariprex contains Aripiprazole 1 mg/ml. Ariprex Dosage:

For Schizophrenia:

Adults-10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.

For Bipolar mania:

Adults- 30 mg, once daily, without regard to food.

 

Side Effects

Headache, constipation, asthenia, nausea, dyspepsia, vomiting, coughing, abdominal pain.

Precaution

Ariprex may be associated with orthostatic hypotension (orthostatic lightheadedness).

Ariprex should be used with caution in patients with known cardiovascular disease (myocardial infarction or ischaemic heart disease, heart failure or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications).

Seizures occurred in aripiprazole-treated patients. As with other antipsychotic drugs, aripiprazole should be used cautiously in patients with Alzheimer\\\'s dementia.

Ariprex is not approved for the treatment of patients with dementia-related psychosis.

Ariprex

Interaction

Caution should be exercised when aripipazole is taken in combination with other centrally acting drugs and alcohol. Carbamazepine could cause an increase in aripiprazole clearance and lower blood levels. Ketoconazole, quinidine, fluoxetine or paroxetine can inhibit aripiprazole elimination and cause increased blood levels.

Pregnancy Lactation use

Ariprex should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast-feed an infant if they are taking aripiprazole.

Contraindication

Ariprex is contraindicated in patients who are hypersensitive to it or to any component of this product.

Special Warning

 

Acute Overdose

Ariprex at doses up to 1080 mg causes no fatalities. The signs and symptoms observed with aripiprazole overdose included nausea, vomiting, asthenia, diarrhea, and somnolence.

Interaction with other Medicine

Caution should be exercised when aripipazole is taken in combination with other centrally acting drugs and alcohol. Carbamazepine could cause an increase in aripiprazole clearance and lower blood levels. Ketoconazole, quinidine, fluoxetine or paroxetine can inhibit aripiprazole elimination and cause increased blood levels.

Storage Condition