Aprolam Tablet is manufactured by Pacific Pharmaceuticals Ltd. Aprolam Tablet contains 0.25 mg Alprazolam. It is Benzodiazepine sedatives class drug.
Aprolam is a triazolo analogue of the 1,4-benzodiazepine class of drugs. It is an anxiolytic with hypnotic and anticonvulsive properties. Aprolam is presumed to produce its effects via interacting with the Gamma Aminobutyric Acid (GABA) - benzodiazepine receptor complex. Like all benzodiazepines, it causes a dose related CNS depressant activity varying from mild impairment of task performance to hypnosis.
- * Anxiety disorder
- * Short term relief of anxiety
- * Anxiety associated with depression
- * Panic disorder, with or without agoraphobia.
|Therapeutic Class:||Benzodiazepine sedatives|
|Manufacturer:||Pacific Pharmaceuticals Ltd|
|Last Updated:||November 22, 2020 at 6:15 pm|
Table Of contents
Aprolam contains Alprazolam 0.25 mg. Aprolam Dosage:
Treatment should be initiated with a dose of 0.25 to 0.5 mg three times daily. Depending on the response, dose may
be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. The maximum dose should not
exceed 4 mg/day. Occasional patients with panic disorder may need as much as 10 mg a day to achieve a
successful response and in these cases periodic reassessment and consideration of dosage adjustment is required.
Dosage should be individualized for maximum beneficial effect with a lowest possible dose. If side-effects occur at
starting dose, dose may be lowered. When discontinuing therapy, dosage should be reduced gradually by no more
than 0.5 mg every three days.
In elderly patients or in patients with advanced liver disease, the usual starting dose is 0.25 mg, two or three times
daily and may be gradually increased if needed and tolerated. Safety and effectiveness of Aprolam in individuals
below 18 years of age have not been established.
Aprolam XR 1 should be administered once daily, preferably in the morning by patients who are on multiple dosage
regimen of Aprolam 0.25/0.5 mg. The tablets should be taken intact, they should not be chewed, crushed, or broken.
Side effects, if occur, are generally observed at the beginning of therapy and usually disappear upon continued medication. The most frequent side effects are drowsiness and light headedness. The other side effects, that may occur include depression, headache, confusion, dry mouth, constipation etc.
Because Aprolam may produce psychological and physical dependence, increment of dose or abrupt discontinuation of Aprolam therapy should not be done without physician's advice. Duration of therapy must be determined by the physicians. Aprolam should be administered with caution to patients with hepatic or renal disease, chronic pulmonary insufficiency or sleep apnea.
Aprolam produces additive CNS depressant effects when co-administered with other psychotropic medications, anticonvulsants, antihistaminics, ethanol and other drugs which themselves produce CNS depression.
Pregnancy Lactation use
Pregnancy: Aprolam has been categorized in pregnancy category D; that means, it should be avoided in pregnancy.
Lactation: Like other benzodiazepines, Aprolam is assumed to be excreted in breast milk. Therefore, nursing should not be undertaken by mothers who must use Aprolam.
Contraindicated in patients with hypersensitivity to alprazolam or other benzodiazepines. Aprolam is also contraindicated in patients with myasthenia gravis, acute narrow angle glaucoma, during pregnancy and also in infants.
Use in Children: Safety and efficacy of Aprolam in patients under the age of 18 years has not been established.
Manifestations of Aprolam over dosage include somnolence, confusion, impaired coordination, diminished reflexes and coma. In such cases of over dosage general supportive measures should be employed along with immediate gastric lavage.
Interaction with other Medicine
The CNS-depressant action of Aprolam may be aggravated by concomitant use of other psychotropic drugs, anticonvulsants, antihistaminics, alcohol and oral contraceptives.
Aprolam tablets should be stored in a cool and dry place, protected from light and moisture.
What does Aprolam do?
Aprolam is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA).
What is Aprolam used for?
Aprolam is used to treat anxiety disorders and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Alprazolam is in a class of medications called benzodiazepines. It works by decreasing abnormal excitement in the brain.
Is Aprolam a sleeping pill?
Aprolam belong to a class of medicines called benzodiazepines and hydrocodone belongs to the class of medicines called opioids. Both the classes cause sedation (increased tendency to sleep) and respiratory depression (slow and difficult breathing).
What are the side effects of Aprolam?
Common side effects of Aprolam include:
- Headache pain
- Dry mouth
- Impaired coordination
- Increased or decreased appetite
- Memory problems
- Decreased salivation
- Cognitive disorders
- Difficulty speaking
- Weight gain or weight loss
- Nasal congestion
- Decreased or increased libido
- Menstrual disorder
- Difficulty urinating
- Fast heart rate
- Blurred vision
- Low blood pressure (hypotension)
- Increased salivation
What should avoid while taking Aprolam?
Notes for Consumers: Grapefruit juice and grapefruit-containing foods may increase the actions or side effects (such as drowsiness or slowed breathing) of Aprolam. Avoid taking Aprolam with grapefruit juice (or grapefruit) whenever possible, and do not increase your intake of grapefruit while taking Aprolam.
Does anyone take Aprolam daily?
People stop feeling the effects of Aprolam long before it leaves the body, which is why it is often taken more than once a day. It's important to take it as prescribed. Taking too many doses can lead to dependence and accidental overdose.
Is Aprolam a steroid?
Aprolam is a Schedule IV controlled substance and is a common drug of abuse.
Is Aprolam an antidepressant?
Aprolam appears to be an effective antidepressant in the treatment of outpatients who have a diagnosis of major depressive disorder. The authors have reviewed six controlled double-blind studies of Aprolam in the treatment of depression.
Does Aprolam cause liver damage?
Aprolam, like other benzodiazepines, is rarely associated with serum ALT elevations, and clinically apparent liver injury from Aprolam is extremely rare. There have been a few case reports of acute liver injury from Aprolam and recurrence on reexposure has been reported.
Is one .25 Aprolam a day addictive?
Aprolam is a benzodiazepine used to treat anxiety and insomnia. The drug is extremely addictive and should only be used under a doctor's supervision.
Will doctors prescribe Aprolam long-term?
It can be used short-term as a way to offer people immediate relief from their symptoms or as part of a long-term management plan for GAD or panic disorder. Aprolam is often prescribed for panic attacks, which can occur as part of SAD.
How long should I take Aprolam?
Aprolam is a powerful benzodiazepine that is only recommended for use for up to six weeks.
Does Aprolam cause memory loss?
Several research studies have found that chronic or heavy Aprolam use can cause short-term memory loss. This is listed by the National Institutes of Health (NIH) as one of the more serious side effects of Aprolam requiring immediate medical attention.
Does Aprolam help with racing thoughts?
Aprolam may be prescribed to treat symptoms of the manic phase of bipolar disorder. These symptoms include: racing thoughts and speech. high energy.
Can Aprolam help mild depression?
Aprolam is a medication that is approved by the Food and Drug Administration (FDA) to treat anxiety and panic disorders. Aprolam, which is the Aprolam name for the generic drug alprazolam, isn't usually used to treat depression because there are several newer and safer medications available.
Is Aprolam safe to use?
Aprolam is a safe and effective medication when used as directed. Benzodiazepines may produce emotional and/or physical dependence (addiction) even when used as recommended. Physical dependence may develop after 2 or more weeks of daily use.
What is the most Aprolam a doctor can prescribe?
For anxiety disorders, the dosage for adults typically starts at 0.25 mg to 0.5 mg three times per day. A doctor may incrementally increase the dosage to maximize the effect. However, the maximum dosage does not usually exceed 4 mg per day. For panic disorders, the required dose of Aprolam may exceed 4 mg per day.
Can Aprolam make anxiety worse?
Recent studies evaluating the effectivity of Aprolam for anxiety have shown that after just 8 weeks, those that were on a Aprolam prescription had worse anxiety than those who took a placebo. Despite these results, doctors continue to prescribe these benzos for anxiety disorders at an alarming rate.
How long does the Aprolam high last for?
Aprolam has an average half-life of roughly 11 hours in healthy adults. In other words, it takes 11 hours for the average healthy person to eliminate half of the dose of Aprolam.